Bee venom (apitherapy) and arthritis

Dr. Weeks Comment:   bee venom   “apitherapy” has a long and noble tradition in the treatment of arthritis – mostly in Europe and eastern Europe –  Charles Mraz, a wise old Vermont beekeeper and apitherapist taught me this practice in the early 1980s and we formed the American Apitherapy Society then which is still going.   See below for more information on bee vneom and the treatment of arthritis but NEVER use bee venom without having a bee sting kit (benadryl and injectable epinepherine) near by and without being familar with how to use it. 

THE FOLLOWING FROM PUB MED

1:

A new onset of systemic lupus erythematosus developed after bee venom therapy.

Rho YH, Woo JH, Choi SJ, Lee YH, Ji JD, Song GG.

Korean J Intern Med. 2009 Sep;24(3):283-5. Epub 2009 Aug 26.

PMID: 19721868 [PubMed – in process]

2:

Bee venom suppresses LPS-mediated NO/iNOS induction through inhibition of PKC-alpha expression.

Lee KG, Cho HJ, Bae YS, Park KK, Choe JY, Chung IK, Kim M, Yeo JH, Park KH, Lee YS, Kim CH, Chang YC.

J Ethnopharmacol. 2009 May 4;123(1):15-21. Epub 2009 Mar 9.

PMID: 19429333 [PubMed – indexed for MEDLINE]

3:

I accidentally disturbed a beehive in my yard and was stung extensively. It was a frightening experience, but it amazingly seems to have cured my arthritis. Is there any medical basis for this?

[No authors listed]

Mayo Clin Health Lett. 2009 Feb;27(2):8. No abstract available.

PMID: 19367776 [PubMed – indexed for MEDLINE]

4:

Microarray analysis of gene expression profiles in response to treatment with bee venom in lipopolysaccharide activated RAW 264.7 cells.

Jang HS, Chung HS, Ko E, Shin JS, Shin MK, Hong MC, Kim Y, Min BI, Bae H.

J Ethnopharmacol. 2009 Jan 21;121(2):213-20. Epub 2008 Sep 18.

PMID: 18852038 [PubMed – indexed for MEDLINE]

5:

[Clinical randomized study of bee-sting therapy for rheumatoid arthritis]

Liu XD, Zhang JL, Zheng HG, Liu FY, Chen Y.

Zhen Ci Yan Jiu. 2008 Jun;33(3):197-200. Chinese.

PMID: 18807725 [PubMed – indexed for MEDLINE]

6:

Effects of bee venom on the maturation of murine dendritic cells stimulated by LPS.

Lee HS, Chung SH, Song MY, Kim SS, Shin HD, Shim WJ, Han AR, Lee JS.

J Ethnopharmacol. 2008 Nov 20;120(2):215-9. Epub 2008 Aug 23.

PMID: 18790041 [PubMed – indexed for MEDLINE]

7:

The cardiovascular depression caused by bee venom in Sprague-Dawley rats associated with a decrease of developed pressure in the left ventricular and the ratio of ionized calcium/ionized magnesium.

Kang HS, Kim SJ, Lee MY, Jeon SH, Kim SZ, Kim JS.

Am J Chin Med. 2008;36(3):505-16.

PMID: 18543385 [PubMed – indexed for MEDLINE]

8:

JNK pathway is involved in the inhibition of inflammatory target gene expression and NF-kappaB activation by melittin.

Park HJ, Lee HJ, Choi MS, Son DJ, Song HS, Song MJ, Lee JM, Han SB, Kim Y, Hong JT.

J Inflamm (Lond). 2008 May 29;5:7.

PMID: 18507870 [PubMed – in process]

9:

Suppressive effects of bee venom on the immune responses in collagen-induced arthritis in rats.

Kim KW, Shin YS, Kim KS, Chang YC, Park KK, Park JB, Choe JY, Lee KG, Kang MS, Park YG, Kim CH.

Phytomedicine. 2008 Dec;15(12):1099-107.

PMID: 18424106 [PubMed – indexed for MEDLINE]

10:

Bee venom acupuncture for musculoskeletal pain: a review.

Lee MS, Pittler MH, Shin BC, Kong JC, Ernst E.

J Pain. 2008 Apr;9(4):289-97. Epub 2008 Jan 28. Review.

PMID: 18226968 [PubMed – indexed for MEDLINE]

11:

Effects of melittin on the production of matrix metalloproteinase-1 and -3 in rheumatoid arthritic fibroblast-like synoviocytes.

Nah SS, Ha E, Mun SH, Won HJ, Chung JH.

J Pharmacol Sci. 2008 Jan;106(1):162-6.

PMID: 18212480 [PubMed – indexed for MEDLINE]

12:

Bee venom stimulates human melanocyte proliferation, melanogenesis, dendricity and migration.

Jeon S, Kim NH, Koo BS, Lee HJ, Lee AY.

Exp Mol Med. 2007 Oct 31;39(5):603-13.

PMID: 18059136 [PubMed – indexed for MEDLINE]

13:

Apis mellifera venom and melittin block neither NF-kappa B-p50-DNA interactions nor the activation of NF-kappa B, instead they activate the transcription of proinflammatory genes and the release of reactive oxygen intermediates.

Stuhlmeier KM.

J Immunol. 2007 Jul 1;179(1):655-64.

PMID: 17579088 [PubMed – indexed for MEDLINE]

14:

Therapeutic application of anti-arthritis, pain-releasing, and anti-cancer effects of bee venom and its constituent compounds.

Son DJ, Lee JW, Lee YH, Song HS, Lee CK, Hong JT.

Pharmacol Ther. 2007 Aug;115(2):246-70. Epub 2007 May 6. Review.

PMID: 17555825 [PubMed – indexed for MEDLINE]

15:

Osteochondral destruction in the hand following bee stings: a case report of an infant.

Haga N, Masuda K, Takikawa K.

Hand Surg. 2006;11(3):143-5.

PMID: 17405195 [PubMed – indexed for MEDLINE]

16:

Inhibitory effects of melittin on the production of lipopolysaccharide-induced matrix metalloproteinase 3 in human osteoarthritic chondrocytes.

Nah SS, Ha E, Lee HJ, Chung JH.

Toxicon. 2007 May;49(6):881-5. Epub 2006 Dec 28.

PMID: 17303203 [PubMed – indexed for MEDLINE]

17:

[Effect of bee venom on adjuvant induced arthritis in rats]

Luo H, Zuo XX, Li T, Zhang J.

Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2006 Dec;31(6):948-51. Chinese.

PMID: 17213605 [PubMed – in process]

18:

Melittin inhibits inflammatory target gene expression and mediator generation via interaction with IkappaB kinase.

Park HJ, Son DJ, Lee CW, Choi MS, Lee US, Song HS, Lee JM, Hong JT.

Biochem Pharmacol. 2007 Jan 15;73(2):237-47. Epub 2006 Sep 29.

PMID: 17067557 [PubMed – indexed for MEDLINE]

19:

Effects of bee venom on protease activities and free radical damages in synovial fluid from type II collagen-induced rheumatoid arthritis rats.

Suh SJ, Kim KS, Kim MJ, Chang YC, Lee SD, Kim MS, Kwon DY, Kim CH.

Toxicol In Vitro. 2006 Dec;20(8):1465-71. Epub 2006 Jul 28.

PMID: 16989977 [PubMed – indexed for MEDLINE]

20:

Antinociceptive effect and the mechanism of bee venom acupuncture (Apipuncture) on inflammatory pain in the rat model of collagen-induced arthritis: Mediation by alpha2-Adrenoceptors.

Baek YH, Huh JE, Lee JD, Choi do Y, Park DS.

Brain Res. 2006 Feb 16;1073-1074:305-10. Epub 2006 Feb 2.

PMID: 16457792 [PubMed – indexed for MEDLINE]

21:

[Synthesis of peptide fragment of melittin and the function of rheumatoid arthritis cure]

Yu M, Wang Y, Li X, Fang S, Xue J, Song J.

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2005 Oct;22(5):1031-5. Chinese.

PMID: 16294747 [PubMed – indexed for MEDLINE]

22:

[Hymenoptera sting arthropathy as an occupational injury: a case report]

Giannandrea F, Brandi G, Bemardini P.

G Ital Med Lav Ergon. 2005 Apr-Jun;27(2):250-2. Italian.

PMID: 16124540 [PubMed – indexed for MEDLINE]

23:

Inhibitory effect of whole bee venom in adjuvant-induced arthritis.

Lee JY, Kang SS, Kim JH, Bae CS, Choi SH.

In Vivo. 2005 Jul-Aug;19(4):801-5.

PMID: 15999553 [PubMed – indexed for MEDLINE]

24:

Specific immunotherapy-induced Sjögren’s syndrome.

Turkcapar N, Kinikli G, Sak SD, Duman M.

Rheumatol Int. 2005 Dec;26(2):182-4. Epub 2005 Jun 17.

PMID: 15965636 [PubMed – indexed for MEDLINE]

25:

Bee venom induces apoptosis through caspase-3 activation in synovial fibroblasts of patients with rheumatoid arthritis.

Hong SJ, Rim GS, Yang HI, Yin CS, Koh HG, Jang MH, Kim CJ, Choe BK, Chung JH.

Toxicon. 2005 Jul;46(1):39-45.

PMID: 15922390 [PubMed – indexed for MEDLINE]

26:

Effect of bee venom on aromatase expression and activity in leukaemic FLG 29.1 and primary osteoblastic cells.

Kim KS, Choi US, Lee SD, Kim KH, Chung KH, Chang YC, Park KK, Lee YC, Kim CH.

J Ethnopharmacol. 2005 Jun 3;99(2):245-52. Epub 2005 Apr 11.

PMID: 15894134 [PubMed – indexed for MEDLINE]

27:

An Overview of Bee Venom Acupuncture in the Treatment of Arthritis.

Lee JD, Park HJ, Chae Y, Lim S.

Evid Based Complement Alternat Med. 2005 Mar;2(1):79-84.

PMID: 15841281 [PubMed – as supplied by publisher]

28:

General pharmacological profiles of bee venom and its water soluble fractions in rodent models.

Kim HW, Kwon YB, Ham TW, Roh DH, Yoon SY, Kang SY, Yang IS, Han HJ, Lee HJ, Beitz AJ, Lee JH.

J Vet Sci. 2004 Dec;5(4):309-18.

PMID: 15613814 [PubMed – indexed for MEDLINE]

29:

Microarray analysis of gene expression in chondrosarcoma cells treated with bee venom.

Yin CS, Lee HJ, Hong SJ, Chung JH, Koh HG.

Toxicon. 2005 Jan;45(1):81-91.

PMID: 15581686 [PubMed – indexed for MEDLINE]

30:

Antiarthritic effect of bee venom: inhibition of inflammation mediator generation by suppression of NF-kappaB through interaction with the p50 subunit.

Park HJ, Lee SH, Son DJ, Oh KW, Kim KH, Song HS, Kim GJ, Oh GT, Yoon DY, Hong JT.

Arthritis Rheum. 2004 Nov;50(11):3504-15.

PMID: 15529353 [PubMed – indexed for MEDLINE]

31:

Anti-inflammatory effect of bee venom on type II collagen-induced arthritis.

Lee JD, Kim SY, Kim TW, Lee SH, Yang HI, Lee DI, Lee YH.

Am J Chin Med. 2004;32(3):361-7.

PMID: 15344419 [PubMed – indexed for MEDLINE]

32:

ATP in the mechanotransduction pathway of normal human chondrocytes.

Millward-Sadler SJ, Wright MO, Flatman PW, Salter DM.

Biorheology. 2004;41(3-4):567-75.

PMID: 15299287 [PubMed – indexed for MEDLINE]

33:

[Advances in the study of bee venom and its clinical uses]

Liu H, Tong F.

Zhong Yao Cai. 2003 Jun;26(6):456-8. Review. Chinese. No abstract available.

PMID: 14669739 [PubMed – indexed for MEDLINE]

34:

Inhibition of COX-2 activity and proinflammatory cytokines (TNF-alpha and IL-1beta) production by water-soluble sub-fractionated parts from bee (Apis mellifera) venom.

Nam KW, Je KH, Lee JH, Han HJ, Lee HJ, Kang SK, Mar W.

Arch Pharm Res. 2003 May;26(5):383-8.

PMID: 12785734 [PubMed – indexed for MEDLINE]

35:

Acupoint stimulation using bee venom attenuates formalin-induced pain behavior and spinal cord fos expression in rats.

Kim HW, Kwon YB, Ham TW, Roh DH, Yoon SY, Lee HJ, Han HJ, Yang IS, Beitz AJ, Lee JH.

J Vet Med Sci. 2003 Mar;65(3):349-55.

PMID: 12679565 [PubMed – indexed for MEDLINE]

36:

The effect of whole bee venom on arthritis.

Kang SS, Pak SC, Choi SH.

Am J Chin Med. 2002;30(1):73-80.

PMID: 12067099 [PubMed – indexed for MEDLINE]

37:

The water-soluble fraction of bee venom produces antinociceptive and anti-inflammatory effects on rheumatoid arthritis in rats.

Kwon YB, Lee HJ, Han HJ, Mar WC, Kang SK, Yoon OB, Beitz AJ, Lee JH.

Life Sci. 2002 May 31;71(2):191-204.

PMID: 12031688 [PubMed – indexed for MEDLINE]

38:

The analgesic efficacy of bee venom acupuncture for knee osteoarthritis: a comparative study with needle acupuncture.

Kwon YB, Kim JH, Yoon JH, Lee JD, Han HJ, Mar WC, Beitz AJ, Lee JH.

Am J Chin Med. 2001;29(2):187-99.

PMID: 11527062 [PubMed – indexed for MEDLINE]

39:

Antinociceptive effects of bee venom acupuncture (apipuncture) in rodent animal models: a comparative study of acupoint versus non-acupoint stimulation.

Kwon YB, Kang MS, Kim HW, Ham TW, Yim YK, Jeong SH, Park DS, Choi DY, Han HJ, Beitz AJ, Lee JH.

Acupunct Electrother Res. 2001;26(1-2):59-68.

PMID: 11394494 [PubMed – indexed for MEDLINE]

40:

Bee venom pretreatment has both an antinociceptive and anti-inflammatory effect on carrageenan-induced inflammation.

Lee JH, Kwon YB, Han HJ, Mar WC, Lee HJ, Yang IS, Beitz AJ, Kang SK.

J Vet Med Sci. 2001 Mar;63(3):251-9.

PMID: 11307924 [PubMed – indexed for MEDLINE]

41:

Bee venom injection into an acupuncture point reduces arthritis associated edema and nociceptive responses.

Kwon YB, Lee JD, Lee HJ, Han HJ, Mar WC, Kang SK, Beitz AJ, Lee JH.

Pain. 2001 Feb 15;90(3):271-80.

PMID: 11207399 [PubMed – indexed for MEDLINE]

42:

Secreted phospholipase A(2) induces vascular endothelial cell migration.

Rizzo MT, Nguyen E, Aldo-Benson M, Lambeau G.

Blood. 2000 Dec 1;96(12):3809-15.

PMID: 11090064 [PubMed – indexed for MEDLINE]

43:

Mechanotransduction via integrins and interleukin-4 results in altered aggrecan and matrix metalloproteinase 3 gene expression in normal, but not osteoarthritic, human articular chondrocytes.

Millward-Sadler SJ, Wright MO, Davies LW, Nuki G, Salter DM.

Arthritis Rheum. 2000 Sep;43(9):2091-9.

PMID: 11014361 [PubMed – indexed for MEDLINE]

44:

Beekeeper’ arthropathy.

Cuende E, Fraguas J, Peña JE, Peña F, García JC, González M.

J Rheumatol. 1999 Dec;26(12):2684-90.

PMID: 10606383 [PubMed – indexed for MEDLINE]

45:

Venoms, copper, and zinc in the treatment of arthritis.

Caldwell JR.

Rheum Dis Clin North Am. 1999 Nov;25(4):919-28, viiiix. Review.

PMID: 10573766 [PubMed – indexed for MEDLINE]

46:

Effects of petrosaspongiolide M, a novel phospholipase A2 inhibitor, on acute and chronic inflammation.

Garcia-Pastor P, Randazzo A, Gomez-Paloma L, Alcaraz MJ, Paya M.

J Pharmacol Exp Ther. 1999 Apr;289(1):166-72.

PMID: 10087000 [PubMed – indexed for MEDLINE]

47:

A therapeutic bee sting?

Cerrato PL.

RN. 1998 Aug;61(8):57-8. Review. No abstract available.

PMID: 9739302 [PubMed – indexed for MEDLINE]

48:

Melittin binds to secretory phospholipase A2 and inhibits its enzymatic activity.

Saini SS, Peterson JW, Chopra AK.

Biochem Biophys Res Commun. 1997 Sep 18;238(2):436-42.

PMID: 9299527 [PubMed – indexed for MEDLINE]

49:

The antirheumatic drug disodium aurothiomalate inhibits CD4+ T cell recognition of peptides containing two or more cysteine residues.

Griem P, Takahashi K, Kalbacher H, Gleichmann E.

J Immunol. 1995 Aug 1;155(3):1575-87.

PMID: 7543525 [PubMed – indexed for MEDLINE]

50:

Phospholipase A2-activating protein induces the synthesis of IL-1 and TNF in human monocytes.

Bomalaski JS, Ford T, Hudson AP, Clark MA.

J Immunol. 1995 Apr 15;154(8):4027-31.

PMID: 7706741 [PubMed – indexed for MEDLINE]

51:

Persistent nodular lesions caused by “bee-sting therapy”.

Veraldi S, Raiteri F, Caputo R, Alessi E.

Acta Derm Venereol. 1995 Mar;75(2):161-2. No abstract available.

PMID: 7604655 [PubMed – indexed for MEDLINE]

52:

Modulation of alpha 1-acid glycoprotein (AGP) gene induction following honey bee venom administration to adjuvant arthritic (AA) rats; possible role of AGP on AA development.

Yiangou M, Konidaris C, Victoratos P, Hadjipetrou-Kourounakis L.

Clin Exp Immunol. 1993 Oct;94(1):156-62.

PMID: 8403499 [PubMed – indexed for MEDLINE]

53:

Human rheumatoid synovial cell stimulation by the membrane attack complex and other pore-forming toxins in vitro: the role of calcium in cell activation.

Daniels RH, Williams BD, Morgan BP.

Immunology. 1990 Nov;71(3):312-6.

PMID: 2269468 [PubMed – indexed for MEDLINE]

54:

Rheumatoid arthritis synovial fluid phospholipase A2 activating protein (PLAP) stimulates human neutrophil degranulation and superoxide ion production.

Bomalaski JS, Baker D, Resurreccion NV, Clark MA.

Agents Actions. 1989 Jun;27(3-4):425-7.

PMID: 2552770 [PubMed – indexed for MEDLINE]

55:

Bee venom and adjuvant arthritis.

Somerfield SD, Brandwein S.

J Rheumatol. 1988 Dec;15(12):1878. No abstract available.

PMID: 3230576 [PubMed – indexed for MEDLINE]

56:

Honeybees and arthritis: sharpening perspective on a sticky issue.

Panush RS.

J Rheumatol. 1988 Oct;15(10):1461-2. No abstract available.

PMID: 3204596 [PubMed – indexed for MEDLINE]

57:

Bee venom, adjuvant induced disease and interleukin production.

Hadjipetrou-Kourounakis L, Yiangou M.

J Rheumatol. 1988 Jul;15(7):1126-8.

PMID: 3262759 [PubMed – indexed for MEDLINE]

58:

Bee venom melittin blocks neutrophil O2- production.

Somerfield SD, Stach JL, Mraz C, Gervais F, Skamene E.

Inflammation. 1986 Jun;10(2):175-82.

PMID: 3011670 [PubMed – indexed for MEDLINE]

59:

Bee venom and arthritis: magic, myth or medicine?

Somerfield SD.

N Z Med J. 1986 Apr 23;99(800):281-3. No abstract available.

PMID: 3010202 [PubMed – indexed for MEDLINE]

60:

Bee venom and arthritis.

Somerfield SD.

J Rheumatol. 1986 Apr;13(2):477. No abstract available.

PMID: 3014144 [PubMed – indexed for MEDLINE]

61:

Bee venom and adjuvant induced disease.

Hadjipetrou-Kourounakis L, Yiangou M.

J Rheumatol. 1984 Oct;11(5):720. No abstract available.

PMID: 6512799 [PubMed – indexed for MEDLINE]

62:

The concept of anti-inflammatory peptides.

Somerfield SD.

N Z Med J. 1984 May 9;97(755):298-300. No abstract available.

PMID: 6610141 [PubMed – indexed for MEDLINE]

63:

The public’s perceptions and misperceptions of arthritis.

Price JH, Hillman KS, Toral ME, Newell S.

Arthritis Rheum. 1983 Aug;26(8):1023-8.

PMID: 6882478 [PubMed – indexed for MEDLINE]

64:

Bee venom and adjuvant arthritis.

Somerfield SD.

J Rheumatol. 1983 Jun;10(3):522. No abstract available.

PMID: 6887182 [PubMed – indexed for MEDLINE]

65:

[Bee venom containing Forapin in the treatment of mesenchymal diseases of the locomotor system. Report on treatment results in 211 patients]

Mund-Hoym WD.

Med Welt. 1982 Aug 27;33(34):1174-7. German. No abstract available.

PMID: 7132669 [PubMed – indexed for MEDLINE]

66:

Bee venom therapy of adjuvant arthritis.

Tannenbaum H, Greenspoon M.

J Rheumatol. 1982 Jul-Aug;9(4):649. No abstract available.

PMID: 7131471 [PubMed – indexed for MEDLINE]

67:

Effect of honeybee (Apis mellifera) venom on the course of adjuvant-induced arthritis and depression of drug metabolism in the rat.

Eiseman JL, von Bredow J, Alvares AP.

Biochem Pharmacol. 1982 Mar 15;31(6):1139-46.

PMID: 6177321 [PubMed – indexed for MEDLINE]

68:

Adolapin–a newly isolated analgetic and anti-inflammatory polypeptide from bee venom.

Shkenderov S, Koburova K.

Toxicon. 1982;20(1):317-21.

PMID: 7080045 [PubMed – indexed for MEDLINE]

69:

[Drug therapy of rheumatoid arthritis]

Rudyk BI.

Feldsher Akush. 1980;45(6):8-10. Russian. No abstract available.

PMID: 6901677 [PubMed – indexed for MEDLINE]

70:

Anti-arthritic effect of bee venom.

Chang YH, Bliven ML.

Agents Actions. 1979 Jun;9(2):205-11.

PMID: 474306 [PubMed – indexed for MEDLINE]

71:

[Therapeutic properties of bee venom]

Bacq ZM, Lecomte J, Leclercq M.

Rev Med Liege. 1974 Apr 15;29(8):239. French. No abstract available.

PMID: 4826387 [PubMed – indexed for MEDLINE]

72:

Anti-inflammatory property of 401 (MCD-peptide), a peptide from the venom of the bee Apis mellifera (L.).

Hanson JM, Morley J, Soria-Herrera C.

Br J Pharmacol. 1974 Mar;50(3):383-92.

PMID: 4152780 [PubMed – indexed for MEDLINE]

73:

Letter: An anti-inflammatory peptide from bee venom.

Billingham ME, Morley J, Hanson JM, Shipolini RA, Vernon CA.

Nature. 1973 Sep 21;245(5421):163-4. No abstract available.

PMID: 4582672 [PubMed – indexed for MEDLINE]

74:

Effect of bee venom on experimental arthritis.

Zurier RB, Mitnick H, Bloomgarden D, Weissmann G.

Ann Rheum Dis. 1973 Sep;32(5):466-70. No abstract available.

PMID: 4751783 [PubMed – indexed for MEDLINE]

75:

Influence of bee venom in the adjuvant-induced arthritic rat model.

Lorenzetti OJ, Fortenberry B, Busby E.

Res Commun Chem Pathol Pharmacol. 1972 Sep;4(2):339-52. No abstract available.

PMID: 4538551 [PubMed – indexed for MEDLINE]

76:

[Treatment with bee venom]

Gorobets GN.

Feldsher Akush. 1972 May;37(5):38-9. Russian. No abstract available.

PMID: 4482902 [PubMed – indexed for MEDLINE]

77:

The specificity of the anti-hyaluronidase developed in beekeepers serum against bee venom hyaluronidase.

Barker SA, Walton KW, Weston PD.

Clin Chim Acta. 1967 Jul;17(1):119-23. No abstract available.

PMID: 4166652 [PubMed – indexed for MEDLINE]

78:

Standardized bee venom (SBV) therapy of arthritis. Controlled study of 50 cases with 84 percent benefit.

Steigerwaldt F, Mathies H, Damrau F.

Ind Med Surg. 1966 Dec;35(12):1045-9. No abstract available.

PMID: 5332533 [PubMed – indexed for MEDLINE]

79:

[Treatment of patients with spondyloarthritis deformans with bee venom.]

PORIADIN VT.

Kazan Med Zh. 1962 Jul-Aug;4:73-5. Russian. No abstract available.

PMID: 14488023 [PubMed – indexed for MEDLINE]

80:

[Bee venom in the treatment of infectious non-specific (rheumatoid) arthritis.]

PERTSULENKO VA.

Sov Med. 1961 Jun;25:94-101. Russian. No abstract available.

PMID: 13734638 [PubMed – indexed for MEDLINE]

81:

[Use of bee venom in polyarthritis.]

ISTOMINA KV, KONEVTSEVA TV.

Sov Med. 1959 Feb;23(2):133-4. Russian. No abstract available.

PMID: 13646994 [PubMed – indexed for MEDLINE]

82:

[Studies on the effect of bee venom and histamine in formaldehyde arthritis in the rat.]

NEUMANN W, STRACKE A.

Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1951;213(1-2):8-17. Undetermined Language. No abstract available.

PMID: 14869074 [PubMed – OLDMEDLINE]

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Dr. Weeks Comment:   bee venom   “apitherapy” has a long and noble tradition in the treatment of arthritis – mostly in Europe and eastern Europe –  Charles Mraz, a wise old Vermont beekeeper and apitherapist taught me this practice in the early 1980s and we formed the American Apitherapy Society then which is still going.   See…
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