Dr. Weeks’ Comment: As I have taught for the past 20 years, you don’t get to be a living species of plant on our fair earth without having in your make up, anti-cancer, anti-fungal, anti-biotic chemicals. We humans live amidst an elegantly balanced natural “drug store” from which the wisest of cultures have borrowed reverently… native Americans used the willow bark for aspirin whereas dumb westerners driven by the profit motive (patent medicine) extracted the”active ingredient, “salicylic acid” to treat pain while causing death by gastric ulcers… so back the westerners went to the bark to pull out the buffering agent, and gave us “Bufferin”. The Pacific Yew yielded Tamoxifen for cancer, William Nourse’s dairy farm’s gutters in New York produced Nystatin and of course the Brits extracted gin from the juniper and quinine from the cinchona tree bark for protection against malaria while they strode upon world cultures. Now, again, we “discover” what ancient cultures knew all along: the cedar tree has health giving properties too. Read on!
Chemical Compounds in Trees Can Fight Deadly Staph Infections in Humans
ScienceDaily (Feb. 25, 2011) — Most people would never suspect that a “trash tree,” one with little economic value and often removed by farmers due to its ability to destroy farmland, could be the key to fighting a deadly bacterium. Now, a University of Missouri researcher has found an antibiotic in the Eastern Red Cedar tree that is effective against methicillin-resistant Staphylococcus aureus (MRSA), a “superbug” that is resistant to most medications.
“I wanted to find a use for a tree species that is considered a nuisance,” said Chung-Ho Lin, research assistant professor in the MU Center for Agroforestry at the College of Agriculture, Food and Natural Resources. “This discovery could help people fight the bacteria as well as give farmers another cash crop.”
MRSA is an evolving bacterium that is resistant to most medications. For most people, the infection is isolated to the skin. However, it can spread to vital organs causing toxic shock syndrome and pneumonia, especially in people with weakened immune systems. The incidence of disease caused by MRSA bacteria is increasing worldwide. Thirty years ago, MRSA accounted for 2 percent of all staph infections. By 2003, that number had climbed to 64 percent. In 2005, more than 94,000 people developed life-threatening MRSA infections in the United States, according to a Centers for Disease Control report. Nearly 19,000 people died during hospital stays related to these infections.
While the Eastern Red Cedar has few commercial uses, it is present in the U.S. in large numbers and its range extends from Kansas to the eastern United States. An estimated 500 million trees grow in Missouri. Lin began his investigation by building on existing research showing the anti-bacterial potential of chemical compounds derived from the tree.
Lin, George Stewart, professor and department chair of Pathobiology in the College of Veterinary Medicine, and Brian Thompson, postdoctoral fellow in the Bond Life Sciences Center, identified, isolated and tested 17 bioactive compounds and has plans to analyze more compounds. Scientists found that a relatively small concentration of a chemical compound found in the Eastern Red Cedar- 5 micrograms per milliliter — was effective against MRSA. The team tested the compound’s effectiveness against many versions of MRSA in a test tube with promising initial results.
“We found this chemical from the cedar needles, an abundant and renewable resource that can be collected annually,” co-researcher Brian Thompson said. “Because the compound is in the needles, we don’t have to cut down the trees.”
In addition to its potential use in fighting MRSA, researchers found that some chemical compounds in the tree are able to fight and kill skin cancer cells present in mice. It may also be effective as a topical acne treatment. Stewart said the compounds are years away from commercial use, as they must go through clinical trials. The team’s research was presented recently at the International Conference on Gram-Positive Pathogens.