Dr. Weeks’ Comment: Half again as many females than males get PoTS and the HPV vaccine has been suspect for the past 5 years since it creates predictable neurological damage. In addition to other etiological factors, we recommend that clinicians not forget to inquire about whether the person suffering with PoTS might have recently had a HPV vaccination.
“… In a population referred for symptoms of orthostatic intolerance and other symptoms consistent with autonomic dysfunction that began in close temporal association with a quadrivalent HPV vaccination, we identified a 60% prevalence of POTS…”
Orthostatic intolerance and postural tachycardia syndrome as suspected adverse effects of vaccination against human papilloma virus.
Abstract
BACKGROUND:
Infections with human papilloma virus (HPV) can result in cervical, oropharyngeal, anal, and penile cancer and vaccination programs have been launched in many countries as a preventive measure. We report the characteristics of a number of patients with a syndrome of orthostatic intolerance, headache, fatigue, cognitive dysfunction, and neuropathic pain starting in close relation to HPV vaccination.
METHODS:
Patients were referred for orthostatic intolerance following HPV vaccination. Symptoms of autonomic dysfunction were quantified by standardised questionnaire. The diagnosis of postural orthostatic tachycardia syndrome (POTS) rested on finding a sustained heart rate increment of >30min(-1) (>40min(-1) in adolescents) or to levels >120min(-1) during orthostatic challenge.
RESULTS:
35 women aged 23.3±7.1 years participated. Twenty-five had a high level of physical activity before vaccination and irregular periods were reported by all patients not on treatment with oral contraception. Serum bilirubin was below the lower detection limit in 17 patients. Twenty-one of the referred patients fulfilled the criteria for a diagnosis of POTS (60%, 95%CI 43-77%). All patients had orthostatic intolerance, 94% nausea, 82% chronic headache, 82% fatigue, 77% cognitive dysfunction, 72% segmental dystonia, 68% neuropathic pain.
CONCLUSIONS:
In a population referred for symptoms of orthostatic intolerance and other symptoms consistent with autonomic dysfunction that began in close temporal association with a quadrivalent HPV vaccination, we identified a 60% prevalence of POTS. Further work is urgently needed to elucidate the potential for a causal link between the vaccine and circulatory abnormalities and to establish targeted treatment options for the affected patients.
AND
Autonomic dysfunction presenting as postural orthostatic tachycardia syndrome in patients with multiple sclerosis.
BACKGROUND:
Autonomic dysfunction is common in patients suffering from multiple sclerosis (MS) and orthostatic dizziness occurs in almost 50% of these patients. However, there have been no reports on postural orthostatic tachycardia syndrome (POTS) in patients suffering from MS.
METHODS:
The patients were included for analysis in this study if they had POTS with either a prior history of MS or having developed MS while being followed for POTS. Postural orthostatic tachycardia (POTS) is defined as symptoms of orthostatic intolerance(>6 months) accompanied by a heart rate increase of at least 30 beats/min (or a rate that exceeds 120 beats/min) that occurs in the first 10 minutes of upright posture or head up tilt test (HUTT) occurring in the absence of other chronic debilitating disorders. We identified nine patients with POTS who were suffering from MS as well. Each of these patients had been referred from various other centers for second opinions.
RESULTS:
The mean age at the time of diagnosis of POTS was 49+/-9 years and eight of the 9 patients were women. Five patients (55%) had hyperlipidemia, 3 (33%) migraine and 2 (22%) patients had coronary artery disease and diabetes each. Fatigue and palpitations (on assuming upright posture) were the most common finding in our patients (9/9). All patients also had orthostatic dizziness. Syncope was seen in 5/9(55%) of patients. Four patients (44%), who did not have clear syncope, were having episodes of near syncope. The presence of POTS in our study population resulted in substantial limitation of daily activities. Following recognition and treatment of POTS, 6/9(66%), patients were able to resume daily activities of living. Their symptoms (especially fatigue and orthostatic intolerance) improved. The frequency and severity of syncope also improved. Three (33%) patients failed to show a good response to treatment.
CONCLUSION:
Patients suffering from MS may manifest autonomic dysfunction by developing POTS. Early recognition and proper management may help improve the symptoms of POTS.
Joe Mercola described similar bizarre neurological consequences of Gardasil vaccination here
HPV Vaccine Linked to Nervous System Disorder and Autoimmunity
At the end of 2013, the human papillomavirus (HPV) vaccine Gardasil had generated nearly 30,000 adverse reaction reports to the US government, including 140 deaths.1
This is probably a gross underestimate, because, although a federal law was passed in 1986 (the National Childhood Vaccine Injury Act) mandating that doctors and other vaccine providers report serious health problems or deaths that occur after vaccination to the Vaccine Adverse Events Reporting System (VAERS), there are no legal penalties for not reporting.
This means that the US uses a passive reporting system, with the vast majority of vaccine reactions never being reported. When doctors do report Gardasil vaccine reactions, for example, most of them do not send the report to VAERS but make reports directly to Merck (the vaccine’s maker).2
Health problems associated with the Gardasil vaccine include immune-mediated inflammatory neurodegenerative disorders, suggesting that something is causing the immune system to overreact in a detrimental way””sometimes fatally.
Seasoned journalist Katie Couric recently gave airtime to two mothers whose daughters’ health suddenly deteriorated after Gardasil shots, prompting an inappropriate smear campaign against her. What it should have done was further encourage an open, honest discussion about the safety of this vaccine, which appears to be highly questionable.
The truth is that a growing body of medical literature is showing the HPV vaccine is linked to nervous and immune system disorders in some young women and girls. If you’re a parent or a young person being encouraged to give this vaccine to your child or get it yourself, you deserve to know what the research really shows.
Two Studies Link HPV Vaccine with Nervous and Immune System Disorders
In one recent case study published in the Journal of Investigative Medicine,3researchers described the case of a 14-year-old girl who developed postural orthostatic tachycardia syndrome (POTS) with chronic fatigue two months following Gardasil vaccination.
POTS is a disorder of the autonomic nervous system, which controls functions in your body such as your heart rate, balance, digestion, bladder control and sleep. While rare, incidence of POTS appears to be increasing and emerging evidence suggests it may be an autoimmune disorder, in which your immune system mistakenly attacks your own body. As reported by GreenMedInfo:4
“Immunization is considered a potential pathway for this pathogenesis via something called ‘molecular mimicry’ — where antibodies against vaccine components ‘cross-react’ with innate body proteins.”
The study authors also suggested that in this case the POTS fulfilled the criteria for a condition known as autoimmune/auto-inflammatory syndrome induced by adjuvants (ASIA). ASIA was first identified in 2011, and has highlighted the underlying mechanisms of how vaccines, and particularly their adjuvants (such as aluminum), may be triggering disease.
In the Journal of Autoimmunology,5 Dr. Yehuda Schoenfeld described the diagnostic criteria for ASIA, which includes “weakness, anxiety, rashes, chronic fatigue, sleep disorders, and the onset of a range of autoimmune diseases from Systemic Lupus Erythematosis to Rheumatoid Arthritis — sometimes years after an initial reaction.”6
and the Original Skeptical Raptor piles on the scientific evidence here.
HPV VACCINE ADVERSE EVENTS – THIS TIME, POTS
April 4th 2015
I make my goal that if you’re going to make some claim that goes against the scientific consensus, then it must be done with high quality evidence, preferably published in a high quality medical or scientific journal. It better be peer reviewed. And it better be good research.
Even if the evidence meets that standard, there is an hierarchy of published evidence from meta- or systematic-reviews at the very top, and junk science published in pseudoscience-pushing websites at the bottom. But there is a range of scientific scholarship, and sometimes, even if an article is published in a top quality journal, the results may be misinterpreted, or even be poorly analyzed.
Case report study about the HPV vaccine
The original HPV quadrivalent vaccine, known as Gardasil (or Silgard in Europe), can prevent infection by human papillomavirus, substantially reducing the risk of these types of cancers. An HPV bivalent vaccine, known as Cervarix, is used in some countries, but only provides protection again two of the subtypes most associated with cervical cancer.
So let’s be clear. All forms of the HPV vaccine prevent cancer, one of the handful of things one can do to actually prevent cancer. But still, the antivaccine cult claims numerous HPV vaccine adverse events that are never supported by real research in real clinical or epidemiological studies.
Recently, there was a report in the journal Vaccine, a genuinely high quality journal that reported a diagnosis of postural orthostatic tachycardia syndrome (POTS, a condition in which a change from the supine position to an upright position causes an abnormally large increase in heart rate, called tachycardia) in 21 out of 35 women who received the HPV vaccine within some unknown time period.
The authors then conclude that:
In a population referred for symptoms of orthostatic intolerance and other symptoms consistent with autonomic dysfunction that began in close temporal association with a quadrivalent HPV vaccination, we identified a 60% prevalence of POTS. Further work is urgently needed to elucidate the potential for a causal link between the vaccine and circulatory abnormalities and to establish targeted treatment options for the affected patients.
What does Dr. Diane Harper, M.D., the world authority on the HPV vaccine have to say about it?