Dandelion root for cancer

Dr. Weeks’ Comment:  and what is more powerful than a root?   You are correct: the SEED!  (See the end of this post for helpful solutions)

 

Scientists Find Root That Kills 98% Of Cancer Cells In Only 48 Hours

 

 SOURCE  https://globalwarming-arclein.blogspot.ca/2017/12/scientists-find-root-that-kills-98-of.html

A quick refresher here. Dandelion is powerfully indicated for cancer therapy and it is also a pro health protocol.

Anyone coming off chemo needs to max on the tea to encourage a positive response.  The pause should be short and slowly building up the dosage is indicated here rather than jumping right in.

What i find attractive is that you can harvest it yourself and use it to determine results.

At the same time you need to be careful.  It alters blood chemistry and will conflict with other protocols. Be you own scientist. …
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Scientists Find Root That Kills 98% Of Cancer Cells In Only 48 Hours

http://nativestuff.us/2017/06/scientists-find-root-that-kills-98-of-cancer-cells-in-only-48-hours/

Scientists Find Root That Kills 98% Of Cancer Cells In Only 48 Hours: This root has been used medicinally since ancient times for its various health benefits. However, the most powerful benefit to come out of this common weed is something that medical researchers are super excited to have “discovered” – which is its potential to cure cancer! This potent root builds up blood and immune system- cures prostate, lung, and other cancers better than chemotherapy. According to Dr. Carolyn Hamm from the Windsor Regional Cancer Centre in Ontario, Canada, dandelion root extract was the only thing that helped with chronic myelomonocytic leukemia. This form of cancer typically affects older adults. John Di Carlo, who at the time was a 72-year old cancer patient at the hospital, was sent home to live out his final days after all efforts failed to treat his leukemia.

He told CBC News that he was advised to drink dandelion root tea as a last ditch effort. Perhaps it should have been the first option offered in his treatment plan, as his cancerwent into remission only four months later! His doctors attributed this to the dandelion tea that he drank. Recent studies have shown that dandelion root extract can work very quickly on cancer cells, as was evidenced in Di Carlo’s case. Within 48 hours of coming into contact with the extract, cancerous cells begin to disintegrate. The body happily replaces these with healthy new cells. Further studies have concluded that the extract also has anti-cancer benefits for other types of cancer, including breast, colon, prostate, liver, and lung cancer! Dandelion root tea may not taste as pleasant as other teas, but it’s certainly more pleasant than living with the side effects of chemotherapy or radiation treatments. Traditional cancer therapies harm the immune system by killing all cells, even the healthy ones. Dandelion root has the opposite effect – it actually helps boost your immune system and only targets the unhealthy cells. It’s definitely a win-win situation! Dr. Hamm warns, however, that dandelion root extract can negatively impact the effects of chemotherapy. It’s always best to consult with your doctor, and let them know any and all supplements or foods that you are consuming on a regular basis. Even if you don’t have cancer, eating the greens or drinking dandelion tea can still give you great health! For example, the roots and stems of dandelion can help fight diabetes. It does this by stimulating the pancreas to produce insulin, which in turn stabilizes the spikes in blood sugar levels. 

for the rest of the story – click here

 

NOW…HERE IS THE SCIENCE ON DANDELION and CANCER

2017 Sep;93:1010-1017. doi: 10.1016/j.biopha.2017.07.007. Epub 2017 Jul 14.

Dandelion root extract suppressed gastric cancer cells proliferation and migration through targeting lncRNA-CCAT1.

Abstract

Gastric cancer (GC) is one of the most common tumors worldwide. Standard treatment after early detection involves surgical excision (recurrence is possible), and metastatic gastric cancer is refractory to immuno-, radio-, and most harmful chemotherapies. Various natural compounds have shown efficacy in killing different cancers, albeit not always specifically. In this study, we show that dandelion root extract (DRE) specifically and effectively suppresses proliferation and migration in human gastric cells without inducing toxicity in noncancerous cells. Long noncoding RNAs (lncRNAs) are known to promote tumorigenesis in many cancer types. Here, we showed that the lncRNA colon cancer-associated transcript-1 (CCAT1) was down-regulated in dandelion-treated GC cells. Furthermore, downregulation of CCAT1 inhibited proliferation and migration of gastric cells. We also found that DRE exerted its function in GC cells partially through targeting CCAT1. This data will provide a basis on which further research in cancer treatment through DRE can be executed.

 

2.

2016 Nov 8;7(45):73080-73100. doi: 10.18632/oncotarget.11485.

Dandelion root extract affects colorectal cancer proliferation and survival through the activation of multiple death signalling pathways.

Abstract

Dandelion extracts have been studied extensively in recent years for its anti-depressant and anti-inflammatory activity. Recent work from our lab, with in-vitro systems, shows the anti-cancerpotential of an aqueous dandelion root extract (DRE) in several cancer cell models, with no toxicity to non-cancer cells. In this study, we examined the cancer cell-killing effectiveness of an aqueous DRE in colon cancer cell models. Aqueous DRE induced programmed cell death (PCD) selectively in > 95% of colon cancer cells, irrespective of their p53 status, by 48 hours of treatment. The anti-cancer efficacy of this extract was confirmed in in-vivo studies, as the oral administration of DRE retarded the growth of human colon xenograft models by more than 90%. We found the activation of multiple death pathways in cancer cells by DRE treatment, as revealed by gene expression analyses showing the expression of genes implicated in programmed cell death. Phytochemical analyses of the extract showed complex multi-component composition of the DRE, including some known bioactive phytochemicals such as α-amyrin, β-amyrin, lupeol and taraxasterol. This suggested that this natural extract could engage and effectively target multiple vulnerabilities of cancer cells. Therefore, DRE could be a non-toxic and effective anti-cancer alternative, instrumental for reducing the occurrence of cancer cells drug-resistance.

3.
2012 Oct;41(7):1039-47. doi: 10.1097/MPA.0b013e31824b22a2.

Selective induction of apoptosis and autophagy through treatment with dandelion root extract in human pancreatic cancer cells.

Abstract

OBJECTIVES:

Pancreatic cancer has a 100% mortality rate; the aim of this study is to evaluate the efficacy of dandelion root extract (DRE) in inducing apoptosis and autophagy in aggressive and resistant pancreatic cancer cells.

RESULTS:

BxPC-3 and PANC-1 pancreatic cells were sensitive to aqueous DRE. This extract induces selective apoptosis in a dose- and time-dependent manner. Dandelion root extract caused the collapse of the mitochondrial membrane potential, leading to prodeath autophagy. Normal human fibroblasts were resistant at similar doses.

CONCLUSIONS:

We demonstrate that DRE has the potential to induce apoptosis and autophagy in human pancreatic cancer cells with no significant effect on noncancerous cells. This will provide a basis on which further research in cancer treatment through DRE can be executed.

4.
2012;7(2):e30604. doi: 10.1371/journal.pone.0030604. Epub 2012 Feb 17.

Efficient induction of extrinsic cell death by dandelion root extract in human chronic myelomonocytic leukemia (CMML) cells.

Abstract

BACKGROUND:

Chronic Myelomonocytic Leukemia (CMML) is a heterogeneous disease that is not only hard to diagnose and classify, but is also highly resistant to treatment. Available forms of therapy for this disease have not shown significant effects and patients rapidly develop resistance early on in therapy. These factors lead to the very poor prognosis observed with CMML patients, with median survival duration between 12 and 24 months after diagnosis. This study is therefore centered around evaluating the selective efficacy of a natural extract from dandelion roots, in inducing programmed cell death in aggressive and resistant CMML cell lines.

METHODOLOGY/PRINCIPAL FINDINGS:

To confirm the induction of programmed cell death in three human CMML cell lines, nuclear condensation and externalization of the phosphatidylserine, two main characteristics of apoptosis, were detected using Hoechst staining and annexin-V binding assay. The induction of another mode of cell death, autophagy, was determined using a monodansylcadaverine (MDC) stain, to detect the formation of autophagy vacuoles. The results from this study indicate that Dandelion Root Extract (DRE) is able to efficiently and selectively induce apoptosis and autophagy in these cell lines in a dose and time dependent manner, with no significant toxicity on non-cancerous peripheral blood mononuclear cells. More importantly, we observed early activation of initiator caspase-8, which led to mitochondrial destabilization and the induction of autophagy, suggesting that DRE acts through the extrinsic pathway of apoptosis. The inability of DRE to induce apoptosis in dominant-negative FADD cells, confirms the mechanism of action of DRE in in vitro models of CMML.

CONCLUSION:

The results from this study indicate that natural products, in particular Dandelion RootExtract, have great potential, as non-toxic and effective alternatives to conventional modes of chemotherapy available today.

 

5.

2011;2011:129045. doi: 10.1155/2011/129045. Epub 2010 Dec 30.

The efficacy of dandelion root extract in inducing apoptosis in drug-resistant human melanoma cells.

Abstract

Notoriously chemoresistant melanoma has become the most prevalent form of cancer for the 25-29 North American age demographic. Standard treatment after early detection involves surgical excision (recurrence is possible), and metastatic melanoma is refractory to immuno-, radio-, and most harmful chemotherapies. Various natural compounds have shown efficacy in killing different cancers, albeit not always specifically. In this study, we show that dandelion root extract (DRE) specifically and effectively induces apoptosis in human melanoma cells without inducing toxicity in noncancerous cells. Characteristic apoptotic morphology of nuclear condensation and phosphatidylserine flipping to the outer leaflet of the plasma membrane of A375 human melanoma cells was observed within 48 hours. DRE-induced apoptosis activates caspase-8 in A375 cells early on, demonstrating employment of an extrinsic apoptotic pathway to kill A375 cells. Reactive Oxygen Species (ROS) generated from DRE-treated isolated mitochondria indicates that natural compounds in DRE can also directly target mitochondria. Interestingly, the relatively resistant G361 human melanoma cell line responded to DRE when combined with the metabolism interfering antitype II diabetic drug metformin. Therefore, treatment with this common, yet potent extract of natural compounds has proven novel in specifically inducing apoptosis in chemoresistant melanoma, without toxicity to healthy cells

6.

2011 Jan 7;133(1):86-91. doi: 10.1016/j.jep.2010.09.005. Epub 2010 Sep 16.

Selective induction of apoptosis through activation of caspase-8 in human leukemia cells (Jurkat) by dandelion root extract.

Abstract

AIM OF STUDY:

Dandelion extracts have been used in traditional Native American Medicine and Traditional Chinese Medicine (TCM) for treatment of leukemia and breast cancer; however, the mechanism of action remains unknown. Today, DRE is mainly marketed for management of gastrointestinal and liver disorders. The current study aims to determine the anti-cancer activity of dandelion root extract (DRE) against human leukemia, and to evaluate the specificity and mechanism of DRE-induced apoptosis.

RESULTS:

Aqueous DRE effectively induces apoptosis in human leukemia cell lines in a dose and time dependent manner. Very early activation of caspase-8 and the subsequent activation of caspase-3 indicate that DRE may be inducing extrinsic or receptor-mediated apoptosis. Caspase inhibition rendered this extract ineffective, thus DRE-induced apoptosis is caspase-dependent. Moreover, the dominant-negative FADD cells that are unable to form a complete DISC (death-inducing signaling complex) were resistant to DRE treatment, which further confirms our hypothesis that DRE induces receptor-mediated apoptosis. Interestingly, non-cancerous peripheral blood mononuclear cells (PBMCs) exposed to aqueous DRE under the same treatment conditions as leukemia cells were not significantly affected.

CONCLUSION:

Our results suggest that aqueous DRE contains components that act to induce apoptosis selectively in cultured leukemia cells, emphasizing the importance of this traditional medicine and thus presents a potential novel non-toxic alternative to conventional leukemia therapy.

7.
2008 May;32(5):1085-90.

Evaluation of aqueous extracts of Taraxacum officinale on growth and invasion of breast and prostate cancer cells.

Abstract

Ethnotraditional use of plant-derived natural products plays a significant role in the discovery and development of potential medicinal agents. Plants of the genus Taraxacum, commonly known as dandelions, have a history of use in Chinese, Arabian and Native American traditional medicine, to treat a variety of diseases including cancer. To date, however, very few studies have been reported on the anti-carcinogenic activity of Taraxacum officinale (TO). In the present study, three aqueous extracts were prepared from the mature leaves, flowers and roots, and investigated on tumor progression related processes such as proliferation and invasion. Our results show that the crude extract of dandelion leaf (DLE) decreased the growth of MCF-7/AZ breast cancer cells in an ERK-dependent manner, whereas the aqueous extracts of dandelion flower (DFE) and root (DRE) had no effect on the growth of either cell line. Furthermore, DRE was found to block invasion of MCF-7/AZ breast cancer cells while DLE blocked the invasion of LNCaP prostate cancer cells, into collagen type I. Inhibition of invasion was further evidenced by decreased phosphorylation levels of FAK and src as well as reduced activities of matrix metalloproteinases, MMP-2 and MMP-9. This study provides new scientific data on TO and suggests that TO extracts or individual components present in the extracts may be of value as novel anti-cancer agents.

 

 

Dr. Weeks solution:

Where can seeds and dandelion?  In CORE  – the detoxifying whole crushed organic seed drink offering the powerful blend – milk thistle seed, cranberry seed, black cumin seed  and the following greens:  dandelion, kale, aloe vera, Chlorophyllin, chlorella, spirolina and wheat grass.

BUT WILLIAM SHAKESPEARE taught us this centuries ago – we should honor the lowly weed, the bane of your lawn’s existence – the target of your plague creating glyphosate tsunami (RoundUp™)  – the sunlike dandelion:

 

From a post in 1993:

“… Perhaps this is because they still listen to their great bard, William Shakespeare, who sets the “natural remedy” tone throughout many of his writings but nowhere so eloquently as in Scene Three of Romeo and Juliet. Let’s listen in on Friar Laurence who is out gathering medicinal plants and musing about their qualities:

 

The grey”‘eyed morn smiles on the frowning night, 

Chequering the eastern clouds with streaks of light,

And flecked darkness like a drunkard reels,

From forth the day’s path and Titan’s firey wheels.

Now, ere the sun advance his burning eye,   

The day to cheer and night’s dank dew to dry,

I must up”‘fill this osier cage of ours      

With baleful weeds and precious juiced flowers.                                

The earth that’s Nature’s mother is her tomb,  

What is her burying grave, that is her womb.

And from her womb, children of diverse kind    

We sucking on her natural bosom find.          

Many for many virtues excellent;   

None but  for some, and yet all different.

O, mickle is the powerful grace that lies     

In herbs, plants, stones and their true qualities;

For nought so vile that on the earth does live     

But to the earth some special good doth give.

For nought so good but strained from that  fair use,    

Revolts from true birth, stumbling on abuse.

Virtue, itself, turns to vice being misapplied         

And vice sometimes by action dignified.

Within the infant rind of this small flower     

Poison hath residence and medicine power.

For this, being smelt, with that part cheers each part.    

Being tasted, slays all senses with the heart.

Two such opposed kings encamp them still.  

In man as well as herbs, grace and rude will

And where the worse is predominant,    

Full soon the canker death eats up that plant.

 

“EAT YOUR SEEDS AND EAT YOUR WEEDS!!”

 

(MY LOVE TO MY DEAR SISTER BEATRICE  WHO FED ME “WEEDS AND SEEDS” SINCE HIGH SCHOOL.)

 

 

 

 

 

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Dr. Weeks’ Comment:  and what is more powerful than a root?   You are correct: the SEED!  (See the end of this post for helpful solutions)   Scientists Find Root That Kills 98% Of Cancer Cells In Only 48 Hours    SOURCE  https://globalwarming-arclein.blogspot.ca/2017/12/scientists-find-root-that-kills-98-of.html A quick refresher here. Dandelion is powerfully indicated for cancer therapy and…
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