Environmental Pollutants Panel
Chemicals in the report include metabolites of:
- Xylene
Xylene, a ubiquitos petrochemical solvent, is first oxidized via p450 enzymes then conjugated with glycine to for 2- and 3-methylhippurate. - Toluene
- Benzene (Click for references)
- Trimethylbenzene
- Styrene (Click for references)
- Phthalic Acid Esters (Click for references)
Phthalates are used in the manufacture of plastics to allow for flexibility and to soften resins. Not only that, but it is found in everything from makeup to detergents, shampoos to time-released pharmaceutical drugs. This toxin is a well known endocrine disruptor as well as causing neurological and developmental disorders. It can interfere with tryptophan metabolism resulting in an increase in quinolinic acid, a pro-inflammatory and neurotoxic compound. Phthalates have also been implicated in abnormal fetal development, especially in male fetuses. - Parabens (Click for references)
Parabens are a widely used family of preservatives found in many cosmetic, pharmaceutical and industrial products. Parabens have inherent estrogenic and other hormone related activity and have been implicated in the growth and development of human breast cancer cell lines. - A listing of sources of each chemicals tested is provided with the patient’s report.