TWENTY-FIVE CASE HISTORIES
Case History # 1 Bilateral Mammary Tumor
Name: APA Date: October 14, 1971
Age: 24 Sex: Female
Weight: 45 kg Height: 1.60 m
Profession: Home
Major Symptoms: Sharp pain in the left breast,
Previous History: 2 1/2 years ago was operated on to remove a walnut-sized tumor from her left breast. In the last year has noticed another tumor in the same breast,
The tumor in the left breast grew until reaching a rectangular size of’ 4 x 5 cm. The patient feels sharp burning pain in the breast, burning in the nipple, and the pain has spread to the entire upper left extremity. Underwear is bothersome, and she speaks of vague discomfort in the right arm.
Does not smoke, drink or use drugs.
Specific Symptoms: Digestive: lack of appetite, metallic taste in the mouth, bromhydrosis, halitosis, bitter taste in the mouth, nausea and vomiting of bitter food residues.
Cardiovascular: tachycardia, frequent palpitations, numbing of hands and feet. Feet are swollen in the morning.
Genitourinary: pollakiuria, odinomenorrhea, menstruation for 8 days with leukorrhea. Nervous, irritable, has insomnia.
Musculoskeletal: pain in both superior extremities.
Vital signs: BP: 104/68 Pulse: 83/mm Temperature: 36.5º C
Signs: Patient in generally good state of health, does not appear to be as young as she is, white. Physical exploration uncovers hard, painful lymph nodes on each side of the neck, each the size of a chick pea, above the supraclavicular region. The lower edge of the liver is felt to be swollen, painful; Murphy’s maneuver is positive. The patient complains of pain throughout the area of the colon upon palpation.
Diagnosis: Bilateral mammary tumor.
Treatments: 4 sessions of Donatian Therapy, one every 5 days.
Prognosis: Cured. November 15 a mammography was taken which was normal. X-rays of the thorax showed no metastases.
Description of Treatment: The night before treatment, the patient was administered an enema and upon awakening blood and urine samples were taken.
20 IU of insulin mixed with 1 ml Betalin were administered at 2:30 PM. When symptoms of hypoglycemia began at 3:10, 2 tablespoons of Boldocynara, 2 tablespoons of Mucaine, 2 tablets of Carbotiazol and 1 tablet of Cynomel were administered. Then 100 mg of Endoxan were administered IM with 125 mg Reverin, 1/2 ampule of Madribon, 25 mg of PCT, and 3 ml Betalin, concluding with 1 tablet of Roniacol and 1 of nicotinic acid,
At 3:15 PM the therapy point is reached and 50 mg of Endoxan dissolved in 50% hypertonic glucose solution are given IV.
This treatment was repeated every 5 days, with the addition of 1/2 ampule of Oradexon.
The patient was released on November 1/2 of the same year.
Evolution of Treatment: The first treatment was given on October 16.
The principal symptom, sharp pain in the left breast, is approximately 70% less intense. The tumor now measures 2 x 3 cm; the sharp pains and burning have decreased; the burning of the nipple disappeared, as did the pain in the left arm; discomfort from underwear and in the right arm both disappeared.
Digestive: appearance of appetite, disappearance of other symptoms.
Cardiovascular: no longer has tachycardia, palpitations, or numbness in hands and feet. Edema of the feet has also disappeared.
Nervous: no longer irritable, sleeps better.
Musculoskeletal: no longer feels pain in the arms. Physical exploration reveals a smaller tumor and less pain in the left breasts where the tumor measured 4 x 5 cm, it now measures 2 x 3 cm, the volume, consistency and shape are less irregular, the nipple is smaller.
After the second treatment, the sharp burning pain disappeared and upon physical exploration, there is still slight pain in the breast. The tumor measures 0.5 x 1 cm.
After the third treatment, there were no symptoms and no pain upon palpation. The breast is of normal size and the tumor is the size of a lentil. After the final treatment the breast is normal and no tumor is palpated.
Note, 10/26/78: After giving birth twice, the patient still shows no symptoms, or signs.
Case History # 2 Pulmonary carcinoma of the left vertex
Name: R B C Date: 3/3/53
Age: 40 Sex: Male
Weight: 61 kg Height: 1.71 m
Profession: Businessman
Previous History: The patient relates that after a cold the cough persisted, and this is what motivated the visit. The cough began 6 months ago. He consulted a physician who prescribed several medications, but the cough continued to worsen, with the appearance of mucopurulent phlegm and often blood • An x-ray was taken and a dark area was found at the vertex of the left lung.
The cough intensified further and recently the dyspnea has been very accentuated, as has been the case with the hemoptoic expectoration, as well. Faced with this situation, another physician had him undergo radiotherapy, operating to implant radioactive needles. Two ribs of the left hemithorax were removed and the radioactive needles placed in the vertex of the left lung.
The patient’s condition worsened, with increasing pain and dyspnea; he has difficulty in expelling the expectoration which is very sticky; he has lost 25 kg.
The last x-ray shows a metastasis at the base of the right lung, with a continuous fever of between 37.5 and 38°C (see x””ray #1). The patient relates that he has no appetite and that it is very difficult to swallow because his dyspnea increases. The pain in the left medial hemithorax is continuous. The patient smoked very much: 3 packs of cigarettes per day.
Previous illnesses: had malaria in 1943.
Specific symptoms: Digestive. Anorexia, dysphagia.
Respiratory. Very intense dyspnea.
Physical exploration: Three very painful, grape-sized lymph nodes are palpated in each submaxillar region. Two walnut””sized lymph nodes are found in each supraclavivular region. Auscultation of the thorax shows hoarse, creaking, stertor during respiration. The anterior face of the right hemithorax reveals pleural rubbing.
On the posterior face of the thorax, palpation reveals a lack of vocal vibrations in the left hemithorax and a dampening of them in the right. Upon percussion, the base of the right side and all of the left side sound dampened (?matidez). Upon auscultation no respiratiory murmur is heard on the left side, there is creaking stertor. On the right side, the respiratory murmur is only absent at the base; in the rest of the right hemithorax there is hoarse stertor.
Abdomen. There is intercostal retraction and this continues to the abdomen making evident the enormous effort required for breathing.
The respiration of this patient is predominantly abdominal, like that of a newborn infant.
Diagnosis: Pulmonary carcinoma of the left vertex.
Treatment: 25 sessions of Donatian therapy, one per week for 6 months. 48 hours after the application of the first treatment x-ray #2 was taken, already showing some improvement.
On October 15 was released as cured, as x-ray #3 clearly shows.
Evolution of Treatment: The first treatment was given on March 3, 1953. The main signs of the patient are coughing, dyspnea, hemoptoic expectoration, and pain. The result of the first treatment was that the coughing was reduced. as was the dyspnea and the hemoptoic expectoration; the fever disappeared and the patient recovered some of his appetite, since he could swallow better.
Physical exploration. The submaxillary lymph nodes were reduced in volume and less painful. Upon auscultation of the thorax, the creaking stertor are a little less sonorous, the pleural rubbing of the right hemithorax persists on the anterior face of the hemithorax, on the posterior face of the thorax the vocal vibrations are very much diminished, but they have improved on the right side. With percussion, the dull, dampened response is no longer heard on the right side, nor at the vertex of the left lung, though it continues in the rest. Upon auscultation, the respiratory murmur begins to make itself present at the vertex of the left lung, where the creaking stertor are less sonorous; in the rest of this lung and in all of the right the respiratory murmur is already distinguish able and the hoarse stertor of the right lung are diminished.
Abdomen. Intercostal retraction is less, just as In the rest of the abdomen, abdominal respiration, is also less. X-rays are taken and reveal that the base of the right lung has already cleared up as has the vertex of the left. The patient notices satisfactory improvement with each treatment. Finally, at the 24th treatment, none of the symptoms are present and the patient is given one more. X-rays are taken after the last treatment and reveal a perfectly healthy patient, thus corroborating the clinical evidence.
Case History # 3 Metastasis of carcinoma of the left breast to the right
Name: A G de D Date: February 13, 1970
Age: 37 Sex: Female
Weight: 54 kg Height: 1.65
Profession: Secretary
Previous history: On September 23, 1969 the patient underwent a mastectomy with removal of the entire left breast, since biopsy showed the existence of a cirrhous carcinoma. Since then the patient has noticed that In the right breast a node appeared that has gradually grown in size. At present she feels pain in the right breast, the left arm and is slightly confused. The patient’s father died of cancer.
Specific symptoms: The only thing that calls attention is a weight loss of 5 kg.
Physical exploration. Palpation of the neck reveals several small lymph nodes that are hard and painful. In the supraclavicular region, there are two olivesized lymph nodes on the same side that are very hard and very painful.
In the anterior region of the thorax there is a semi””circular scar that goes from the axilia to the middle of the sternum; the scar is keloid, painful upon palpation and gives the patient a burning sensation. The scar is retracted because it is keloid and is compressing the right arm, which is swollen.
Diagnosis: Metastasis of the carcinoma of the left breast to the right.
Treatment: We administered 14 sessions of Donatian therapy, one per week!
On June 15, 1970 the patient was released as totally cured.
Case History # 4 Malignant melanoma
Name: N F V Date: January 6, 1971
Age: 58 Sex: Male
Weight: 72 kg Height: 1.70 m
Profession: Businessman
Symptoms: The patient relates that 4 years ago he noticed on his left side a wart that grew slowly until reaching a size of 11 by 7 cm, with a fetid suppuration and very bad appearance.
General Data BP: 120/79 Temps 36°c
He has smoked since the age of 28.
Examination: The lesion described by the patient is observed to be situated on the edge of the pelvis.
Diagnosis: Malignant melanoma
Treatment: We applied 14 sessions of Donatlan therapy, one per week.
Three and a half months later the patient was released, totally cured.
Case History # 5 Neuroblastoma with metastases
Name: L E F Date: January 4, 1971
Age: 6 Sex: Female
Weight: 25 kg Height: 1.35 m
Profession: —
Symptoms: Intense pain in both eyes, more intense in the right.
Previous history: The patient’s mother tells us that the disease began a year and a half ago with the appearance of several tumors on the elbow, axilla, occipital region arid around the right orbit. The tumor of the orbital region caused an intense cutting pain that resisted the effects of analgesics. The patient lost her appetite, lost quite a bit of weight, and increasing exophthalmus of the right eye appeared.
The patient was taken to pediatric centers, in one of which she was given radiotherapy and released as incurable. Before radiotherapy, surgery was performed 6 times on the left arm, in the area of the elbow and axilla. Before this, 30 sessions of radiotherapy had been administered: 10 in the right occupital region, 10 in the left occipital region, and 10 in the right orbital region. Before arriving at our clinic the patient received 24 sessions of radiotherapy in the left axilla. There were a total of 6o radiotherapy sessions.
Physical Exploration: Vital signs: BP 70/50 Pulse 120/min
Appears to be 4 years old. Cannot walk. Is cachectic.
On the head there is a tumor of the size of an orange in the right occipital region; another the size of a small lemon in the right temporoparietal region and exophthalmus of the right eye. Appears to be in pain.
In the region of the elbow of the left arm, there is a 3 cm-long scar, apparently of surgical origin. In the axilla of the same arm there is a hard painful tumor the size of an apple.
In the legs there is marked muscular atrophy, there is no particular or achilles tendon reflex.
Diagnosis: Neuroblastoma with metastases
Treatment: We applied 10 sessions of Donatian Therapy over 2 1/2 months. The patient improved noticeably, gained 4 kg and could walk again. The intense pain and tumors disappeared. Died 7 months after treatment because of a metastasis to the brain.
Prognosis: The prognosis that had previously been given was of a few days of survival.
Case History # 6 Basocellular carcinoma of the cervix.
Name: N C de U Date: August 1, 1964
Age: 29 Sex: Female
Weight: 58 kg Height: 1.60 m
Profession: Home
Symptoms: Leukorrhea since more than a year ago. There is polymenorrhea, dysuria, and pruritus in all of the peritoneum. Continuous pain on the soles of the feet, Has lost weight. Was given the Pap test and the result was a basocellular carcinoma. Was given 42 sessions of cobalt therapy. The leukorrhea worsened and took on a fetid odor. Pollakiuria. BP 110/70.
Ceased to menstruate after cobalt treatment,
Gynecological examination: Ulcerated cervix, with bleeding and pain. Clean parametria.
Diagnosis: Basocellular carcinoma of the cervix.
Treatment: We applied 7 sessions of Donatian therapy, one per week.
The patient was examined on March 12, 1965 and found to be clinically healthy; the cervix was free of ulceration and of exophytic development. The patient returned to her previous gynecologist at the Mexican Welfare Institute, who sent the following report:
Name: N C de U MWI N°: 4/33-34923-30
Sex: Female Age: 30
Departments Gynecology Date: March 14, 1965
Report from the Oncology Unit
After gynecological examination the patient N C de U was found to have a cylindrical, retracted and scarred cervix, with no clinical manifestations of tumoral activity. Pap test for confirmation.
Results of Papanicolau: Negative (Group I)
Neoplastic cells were not identified.
The patient is still (I saw her at the end of 1975) in good health.
Evolution of Treatment: First treatment was August 2, 1964. Main symptoms: leukorrhea, pollakiuria, vaginal bleeding.
The results of the first treatment were the lessening of leukorrhea, bleeding and pain on the soles of the feet. After the second session there was a gynecological examination that showed that the cervix was no longer painful, bleeding or ulcerated; the uterus is less red, less swollen and ulceration and bleeding are less. After the fourth treatment the uterus is less painful and there is no leukorrhea, bleeding, or pollakiuria. The ulceration is less and of a different color. After the seventh treatment there is no pain in the uterus nor any exophytic development.
Case History # 7 Epidermoid carcinoma
Name: C M Date: January 20, 1970
Age: 44 Sex: Female
Weight: — Height: 1.65 m
Profession: Home
Previous History: Vaginal bleeding for the last 5 months, pain in the lower part of the abdomen, feels as if a stake was driven through the perineum. Consulted a physician who, after exploration, requested a biopsy that revealed a third degree epidermoid carcinoma.
The patient’s mother died of carcinoma of the uterus.
Signs: Presence of very fetid leukorrhea and moderate, though continuous, vaginal bleeding.
Physical Exploration: The liver is swollen approx. 3 cm on its lower edge. There is moderate splenomegalia.
The gynecological examination revealed a bleeding, ulcerating cervix with a tumor at 9 o’clock extending upwards with a shape like a cauliflower.
Diagnosis: Epidermoid carcinoma.
Treatment: We applied 7 sessions of Donatian therapy, one per week.
On March 14 the patient was released as totally cured, which was ratified by the anatomopathological study annexed.
Evolution of Treatment: The first treatment was on January 21, 1970. The first symptoms of the patient were vaginal bleeding, pain in the lower abdomen, leukorrhea and pain in the area of the liver.
The result of the first treatment was the reduction of bleeding and of the leukorrhea; the pain in the lower abdomen was also reduced. Upon gynecological exploration, the cervix was shown to have a bleeding ulceration and a tumor at 9 o’clock, both of which diminished and were not so sensitive to the touch.
After the fourth treatment, the leukorrhea had almost disappeared completely, just as the vaginal bleeding and the tumor, which in the beginning was the shape of a cauliflower but now is the shape of the uterus. After the seventh and last treatment, the leukorrhea and bleeding have totally disappeared, the pain in the area of the liver has also disappeared and the gynecological exploration of the uterus shows that the ulceration and tumor have disappeared.
The cervix was found to be completely healthy.
Case History # 8 Infiltrating epidermoid carcinoma of the cervix.
Name: F H de L Date: November i6, 1971
Age: 40 Sex: Female
Weight: 45 kg Height: 1.57 m
Profession: Home
Previous History: Subtotal hysterectomy in 1969, because of tumor.
The patient has ”˜oticed that since 6 months ago she has had vaginal bleeding that has become increasingly intense and periodic. There is very fetid leukorrhea, pollakiuria and burning pain in the interior of the vagina. She consulted a gynecologist who requested a biopsy. The biopsy showed an infiltrating class IV epidermoid carcinoma.
Physical Exploration: The cervix is deformed, swollen and bleeding, there are ulcerations at 3 o’clock. Several larger, painful ganglia are palpated on both sides of the neck and in the supraclavicular depressions.
Diagnosis: Infiltrating epidermoid carcinoma of the cervix.
Treatment: We applied 9 sessions of Donatian therapy, one per week. Two months later, the patient was released as totally cured, as is corroborated by the annexed biopsy.
Evolution of treatment: The first treatment was on November 16, 1971.
The main symptoms were intense continuous bleeding, very fetid leukorrhea, pollakiuria and burning pain in the interior of the bladder and vagina. Upon physical exploration painful ganglia were palpated on both sides of the neck and in the supraclavicular depression. Vaginal exploration shows that the cervix is deformed, swollen and bleeding with an ulceration at 3 o’clock.
Results of the first treatment: vaginal bleeding has diminished, as has the leukorrhea and burning pain in the bladder; the swollen lymph nodes in the neck are reduced in size and not as painful; the right supraclavicular lymph node disappeared, none of the swollen lymph nodes could be palpated or caused pain. The cervix already shows no deformity, the edema and bleeding disappeared completely and the ulceration is much smaller. After the fifth and last treatment, there are no clinical signs or symptoms upon vaginal examination; the uterus is clean and of normal shape and consistency; there is no ulceration. A cytological examination and an anatomopathological study are ordered. The cytological examination was normal, and the anatomopathological study was negative for malignant cells. The patient was released as totally cured.
Case History # 9 Uterine and cervical carcinoma
Name: G H de D Date: March 17, 1970
Age: 22 Sex: Female
Weight: 52 kg Height: 1.69 m
Profession: Home
Previous history: The patient tells us that a pain appeared in the lower part of the abdomen as well as a vaginal secretion which caused pruritus and pain during urination; the pain was like pin pricks. There was slight, intermittent bleeding, and though it appeared periodically, it did not coincide with her menstruation. She attributed it to sexual relations with her husband.
She consulted a physician who ordered a biopsy. The biopsy revealed a mixed carcinoma of the cervix with second degree acanthoma predominating.
Symptoms: Pain in the vulva, very fetid leukorrhea, intermittent periodic vaginal bleeding, considerable weight loss (approx. 8 kg), pollakiuria, dysuria, and tenesmus.
BP: 172/78 Pulse: 80/min Temperature: 36.5°C Apparent age: 30.
There is diffuse pain in the lower part of the abdomen. The cervix is deformed, large and painful, hard to the touch, with multiple ulcerations of irregular shape and bleeding. The enormous deviation of the cervix calls attention, and leads to the supposition that the carcinoma is intra- and extra-cervical. The uterus is angled back more than 40°.
Diagnosis:
Uterine carcinoma that has irradiated to the cervix.
Cervical carcinoma – third degree adenocathoma.
Treatment: We administered 9 sessions of Donatian therapy, one per week.
On May 9, before finishing the treatment, vaginal exploration showed that there was no trace of the carcinoma, the cervix had recuperated its normal position, the ulceration had disappeared, and there was no more bleeding.
On April 25, 1970, the Pap test was negative. A biopsy on May 12 showed there was no cancer. The uterus returned to its normal position.
Description of Donatian therapy in this patien:
At the end of 2 1/2 months the patient, who suffered from a uterine carcinoma with irradiation to the cervix, and transformation of the carcinoma into a second degree adenocanthoma, was cured. The first session was on March 18, 1970. Fifteen units of regular insulin were administered via IV, mixed with Chophytol., taking note of the hour (12:50). When the hypoglycemic symptoms appeared, Urovalidin tablets were administered orally, 2 tablets of Lasix, and 1 50 mg tablet of nicotinic acid, as well. At 13:30 she was given, via lM, 1 ampule of Endoxan Asta, 1 ampule of Madribon, 1 ampule of Pan-Notrin, 4 ml of Primogeston 250 mg/mi. 4 ml of Betalin and 1 ml of Inferon. At 13:45, the therapy point, 125 mg of Reverin, 3 ml of B complex, 5 mg of Acriflavin chlorhydrate, 50 mg of methylene blue, 25mg of Resorcinol and 500mg of hexamethylenetetrainine were administered. The treatment was finished with 50 ml of 50% glucose solution, IV.
Evolution of Therapy: The first treatment was on March 18, 1970.
The results of the first treatment were that the pain in the lower abdomen and vaginal secretion diminished, with subsequent loss of pruritus and pain during urination. Vaginal bleeding and pain in the vulva were also less; the leukorrhea was less fetid. Upon vaginal exploration, the cervix was not as hard, large or painful, and the ulcerations were no longer irregular in shape.
After the fourth treatment the patient showed increased appetite, the pain in the lower abdomen is now very sporadic, the bleeding disappeared completely and the secretion is very slight and not fetid. There is no more pollakiuria, dysuria or tenesmus. The ulcerations are no longer bleeding.
After the ninth and last treatment, the patient has shown a gain in weight, there is no leukorrhea, the pain in the lower abdomen has disappeared, and the cervix appears to be normally shaped, not hard or painful to the touch and the ulcerations have disappeared. A cytological examination was ordered; the results were negative. An anatomopathological study was also ordered and showed negative results for malignant cells. The patient was released In May, totally cured.
Case History # 10 Epidermoid carcinoma
Name: E C S Date: October 12, 1970
Age: 26 Sex: female
Weight: 67 kg Height: 1.66 m
Profession: Home
Previous History: The patient tells us that since her third pregnancy, 8 months ago, she began to have abundant leukorrhea, with burning pain; later she began to have vaginal bleeding. She shows the result of a biopsy where she is diagnosed as having an intra-epithelial carcinoma.
Symptoms: Has lost 10 kg, leukorrhea, as mentioned, continues; periodic bleeding, since 2 months ago.
The cervix is swollen, and a painful mass is palpated in the right parametrium; there is bleeding.
Diagnosis: Second stage epidermoid carcinoma.
Treatment: We administered 13 sessions of Donatian therapy, one per week.
On March 25, 1971, the patient was found to be clinically cured, and this was corroborated by the cytological examination done on March 23. The Pap test was negative for carcinoma; Group II atypical cells, no malignancy.
Case History # 11 Broncogenous carcinoma
Name: R A P Date: May 10, 1958
Age: 50 Sex: Male
Weight: 68 kg Height: 1.75 m
Profession: Farmer
Previous History: The patient tells us that 2 months after having had bronchitis, one day he began to cough and expectorate blood in abundance through the mouth and nose.
He provided us with an x-ray showing a tumor the size of an orange in the base of the right lung.
Has smoked 2 packs of cigarettes per day for the last 20 years; is a chronic alcoholic without being a dipsomaniac.
Physical Exploration: There are creaking and whistling stertors spread throughout both hemithoraxes, but they predominate in the left. The patient is very dyspneic. There are no respiratory murmurs in more than half of the left hemithorax.
Diagnosis: Brocogenous carcinoma
Treatment: The patient underwent 18 sessions of Donatian therapy, one per week. After the fifth the patient began to show signs of improvement.
After the 18th session, physical exploration showed that the patient was cured; x””rays were ordered to corroborate these findings. The x-rays were normal.
Case History # 12 Metastasis from breast carcinoma
Name: C C de T Date: February 11, 1970
Age: 65 Sex: Female
Weight: 48 kg Height: 1.67 m
Profession: Home
Previous History: Two years ago the patient underwent a mastectomy of the right breast because of a cirrhous carcinoma. Three weeks later she noticed that a small tumor had begun to grow in the axilla of the same side.
Present Symptoms: Tumor and pain in the right axilla. The left arm feels larger, and there is periodic paresthesia. There is edema of the upper right extremity and axilla.
Physical Exploration: In the right axillary pyramid there is a hard painful lymph node, approx. 3 cm in diameter. There is a retracted scar that goes from the vertex of the axilla to the area of the breast. The right arm and axilla are increasing in volume. BP: 130/85
Diagnosis: Metastasis, to the lymph nodes, of the right axilla of the already removed carcinoma of the right breast.
Treatment: We administered 8 sessions of Donatian therapy, one per week. The patient was released as cured on July 1, 1970; the tumor, pain and swelling having disappeared.
Evolution of Treatment: The first treatment was on February 11, 1970. The result of the first treatment was that the tumor became smaller and less painful; the left arm no longer showed paresthesis and is markedly less swollen. Upon physical exploration, the palpation of the pyramid, of the right axilla shows that the lymph node is 1 cm less in diameter, not as hard and not as painful.
After the fourth treatment the patient reports a marked improvement of the symptoms mentioned above. This was corroborated clinically with the observation of the markedly smaller size of the tumor.
After the eighth and last treatment, the patient is examined once again and shows no evidence of tumor in the right axilla. There is no swelling and the arm is functioning normally. The patient was released as totally cured on July 1, 1970.
Case History # 13 Prostatic Carcinoma
Name: M RN Date: June 25, 1966
Age: 77 Sex: Male
Weight: 75 kg Height: 1.79 in
Profession: Businessman
Present condition: Hematuria and anuria; has not been able to urinate in the last two days. Hematuria has been almost constant since two months ago.
Specific symptoms: The scarcity of symptoms, besides those already mentioned, calls one’s attention.
Physical Exploration: The patient arrived at our clinic with a Foley catheter. Rectal palpation, in the genupectoral position, reveals a prostate grown to the size of a lemon, of irregular edges, painful and of a wooden consistency.
Diagnosis: Prostatic carcinoma
Treatment: We administered 22 treatments of Donatian therapy, one per week.
On February 22, 1967 the patient was released, cured.
Case History # 14 Malignant tumor of the right breast
Name: R R Date: June 27, 1978
Age: 63 Sex: Female
Weight: 59.5 kg Height: 1.60 m
Profession: Home
Previous History: Since April of this year has noticed a little node in the right breast. She went to see a physician who ordered a biopsy with positive results. Slight pain in the right breast and left arm.
Physical Exploration: Hard painful tumor, the size of an almond in the right breast, a lymph node in the right axilla the size of a bean, hard and painful as well. Vaginal exploration shows it to be slightly painful to the touch, with no secretions and a tiny ulcer at 12 or 1 o’clock. Hypertense. Opacity and reduction of the base of the left lung.
Diagnosis: Malignant tumor of the right breast.
Treatment: We administered 5 large and 5 small treatments of Donatian therapy. The patient was examined again on July 31, 1978 and found to be with no clinical evidence of a tumor in the right breast.
Evolution of Treatment: The first treatment was on June 28, 1978.
The results of the first treatment were that cough, eructation, gases, and cramps lessened. Upon palpation, the right breast was not very painful and the tumor was reduced in size. The vagina was no longer painful to the touch, and the small ulcer had disappeared. Auscultatlon showed that pulmonary ventilation had improved.
Besides the normal sessions of therapy, the patient came to the clinic on the next day for medications specifically directed at the symptoms that she still felt.
After the fourth treatment the patient showed no signs or symptoms. After the last treatment, the Oncodiagnosticator is used and now shows negative results. The patient was released on July 31 of the same year. More recently she has reported perfect health, with no recurrence of symptoms.
Case History # 15 Osteal metastases from mammary carcinoma.
Name: J H de P Date: February 18, 1963
Age: 52 Sex: Female
Weight: 50 kg Height: 1.61 m
Profession: Home
Previous History: Two years ago the patient noticed a node in the right breast which increased in size. She consulted a physician who 4 months later performed a total mastectomy and draining of the axillary lymph nodes.
A month after the operation the patient began to feel pain in the scapula, dorsolumbar area and the left half of the pelvic basin. She consulted the same physician who recommended surgery once again and removed both her ovaries. After this second operation the symptoms became more intense, and she was given a total of 10 sessions of radiotherapy. The patient did not improve and her doctor said he could do nothing more to help her, giving her a prognosis of a few weeks of survival. The biopsy performed for the same physician reveals an undifferentiated first degree epidermoid carcinoma.
The patient now complains of very intense pains in the dorsolumbar area of the spine, in the pelvis and is depressed, feeling she is going to die.
Specific symptoms: The patient has lost 17 kg, since her previous average weight was 67 kg. She describes the pains mentioned above that emanate from deep within, as well as those in the hips and the middle of the body.
Physical exploration: Patient ambulatory, very distraught, emaciated appearance. There is a surgical scar that goes from the vertex of the right axilla to the external edge of the sternum, about 20 cm long. On the abdomen there is another scar that goes from the superior edge of the pubis to the navel, since the patient’s uterus was removed because of multiple fibromatosis in 1956.
Diagnosis: Osteal metastases from mammary carcinoma.
Treatment: We administered 10 treatments of Donatian therapy from February 19 to May 19 of the same year.
On May 29 the patient was examined and physical exploration showed the patient to be clinically healthy. A series of vertebral x-rays was ordered, as well as those of the pelvis and the large bones of the extremeties. The x-rays showed no evidence of osteolytic osteal lesions. The patient weighed 69 kg upon release.
Case History # 16 Seminoma of the left testicle
Name: C V G Date: July i6, 1961
Age: 6o Sex: Male
Weight: 40 Height: 1.74 in
Profession: Barber
Previous History: The patient relates that one month ago he awoke in the middle of the night with a sharp piercing pain in the testicle; since then a tumor has appeared and begun to grow. He consulted various physicians, all of whom suggested that he be operated on, as it was a. case of testicular carcinoma. The patient now weighs 40 kg where two months ago he weighed 84 kg. The tumor is the size of an orange. The intense and continuous pain is not only localized in the testicle but is radiating to the whole body.
Specific Symptoms: The patient has to urinate lying down. The penis is not readily seen, as it is lost in the swollen tissue of the scrotum.
Physical exploration: The left testicle is the size of an orange and is very painful to the touch; the vas deferens has greatly increased in volume up to the inguinal canal. The inguinal region hard, painful, irregular lymph nodes are palpated that are the size of marbles.
Diagnosis: Seminoma of the left testicle with metastasis to the corresponding inguinal lymph nodes.
Treatment: We administered 7 sessions of Donatian therapy. After the second session, there was a marked improvement, with substantial reduction in the size of the tumor.
On October 23 the patient was released; all signs and symptoms had completely disappeared.
Evolution of Treatment: The results of the first treatment were that the pain in the testicle became less intense and intermittent, the testicle was reduced to the size of a lime, the vas deferens was more easily palpated since it had also been reduced in volume, the inguinal lymph nodes were round, less painful, softer and the size of beans. The patient began to feel his appetite return.
After the fourth treatment, the pain that radiated to the whole body was only present in the left testicle, greatly reduced in intensity, and the testicle was reduced to the size of a marble; the vas deferens is no longer inflamed or painful; the inguinal lymph nodes are the size of the head of a nail.
At the time of the last three treatments, and especially the last (the seventh), the patient showed no signs of tumor in the testicle; on palpation it was found to be normal, not painful, and with its other normal characteristics; the inguinal lymph nodes disappeared and showed no signs or symptoms. The patient was released in October of the same year, completely cured.
Case History # 17 Lymphocytic lymphoma.
Name: M T A Date: April 23, 1971
Age: 70 Sex: Female
Weight: 61 Height: 1.59 m
Profession: home
Previous history: Had a total hysterectomy 18 years ago. Menopause occurred at 45, after having given birth to 9 children.
Piercing pain in the left cheek began in October of 1970; the patient’s face began to swell after the onset of pain; as it swelled, the cheek became very hard.
Initially the pain was local, but later it radiated to all of the head and the teeth, to the point where it was no longer possible to chew food. Since the tumor continued to grow, the patient went to the Oncology Institute where she was operated on and the tumor was removed. Biopsy revealed that it was a not very differentiated stage II lymphocytic lymphoma.
A few weeks later the swelling began again in the face, the tumor developed and painful lymph nodes appeared in the left axilla.
Physical Exploration: Tumor in the region of the left cheek, ulcerated and producing a creamy yellow liquid with a fetid odor. The tumor reaches the lateral face of the nasal pyramid and is the size of a walnut. There are swollen lymph nodes in the submaxillary region on both sides that are hard and painful.
Fourth degree Systolic murmur in the aortic focus. BP 178/106
Diagnosis: Second degree lymphocytic lymphoma.
Treatment: We administered 10 sessions of Donatian therapy, one per week. The patient was released on July 10, 1971; the attached biopsy reveals the absence of malignant tissue.
Evolution of treatment: The first treatment was on April 23, 1971.
The results of the first treatment were that the pain was less, as was the swelling; the ulcer changed color and oozed less; the tumor was also smaller. Upon physical exploration, the submaxillary lymph nodes were not as hard or painful, as was the case with those in the left axilla.
After the fourth treatment, the ulcer on the left cheek showed the formation of new epithelial tissue, the pus was no longer yellowish or fetid and the tumor was the size of a marble; nor were those of the right submaxillary region; the lymph nodes of the left submaxillary region were still present but very small.
After the eighth treatment the patient showed no more symptoms. After the last two treatments, the histopathological examination reported an absence of malignant neoplastic tissue, with which the patient was released, totally cured, on July 10 of that same year.
Case History # 18 Thyroid carcinoma
Name: N G Z Date: April 30, 1962
Age: 52 Sex: Female
Weight: 37 kg Height: 1.60 m
Profession: home
Previous history: Two years ago a tumor appeared on the left side of the thyroid glands, that sometimes burned and caused the patient pain. In two months the tumor grew to the size of an orange. The local doctor operated, after which she felt well for about a week. Then the tumor and symptoms appeared again but with more intensity. She came to consult a specialist who prescribed radiotherapy.
The radiotherapy was of very high voltage, with two tangential fields; the patient received a total of 2200 r in each field at 220 kv and 15 mA, using a 0.5 mm Copper filter.
Subsequently the patient worsened and the surgeons and radiologists considered her incurable.
The patient arrived at our clinic on April 30, 1962, with more intense pain; she could not chew, there was dysphagia and dysphonia. She had lost 10 kg in the last 3 months.
Physical Exploration: A tumor is palpated under the left maxilla. The patient cannot open her mouth very well. The tumor takes up a large part of the neck and is of a wooden consistency; it is attached to the trachea and is approximately 9 cm long by 6 cm wide, and very painful. BP 145/85
Diagnosis: Thyroid carcinoma
Treatment: We administered 20 sessions of Donatian therapy, May 1 to July 31, 1963.
From the 15th treatment on, the patient complained of no discomfort; the tumor had disappeared. Upon completion of the treatment, the patient was released, totally cured.
Case History # 19 Gastric carcinoma
Name: B T C Date: June 9, 1972
Age: 67 Sex: Female
Weight: 63 kg Height: 1.65 m
Profession: home
Previous history: Menopause occurred at the age of 50, after having had 5 children. The patient tells us that upon returning from a vacation she began to feel pain in the stomach, with nausea and vomiting of phlegm, as well as gradual loss of appetite. She consulted a physician who prescribed Melox. The pain disappeared, but she continued to have no appetite. Several weeks elapsed in this state, until the same symptoms reappeared. She consulted another physician who ordered a gastroduodenal series of x-rays and the diagnosis was gastric carcinoma.
Symptoms: Complete anorexia, continuous piercing pain in the epigastrium which causes nausea and vomiting; upon vomiting the pain disappears or becomes weaker but returns full force minutes later.
Physical Exploration: There is splenomegalia, the epigastrium is very painful. The x-ray with the date May 30, 1972 shows an exophytic growth which affects the major and minor curves in the medial third of the longitudinal diameter of the stomach.
Diagnosis: Second degree (Borman’s classification) gastric carcinoma.
Treatment: We administered 11 sessions of Donatian therapy, one per week. Another gastroduodenal series of x-rays was taken on July 25, 1972, when the treatment had not yet been completed and the patient already had a normal stomach. She was released on August 30, 1972 totally cured.
Evolution of Treatment: The first treatment was on June 9, 1972. As a result of the first treatment, the pain in the epigastrium and the vomiting disappeared; the nausea persisted but with less intensity. After the fifth treatment, the patient recovered her appetite, though the nausea persisted. The patient reports that the pain only recurred once, but with less intensity. After the tenth treatment the patient showed no symptoms, but a gain in weight. After the eleventh treatment another gastroduodenal x-ray series was ordered which confirmed her stomach to be normal.
Case History # 20 Epidermoid carcinoma with metastasis
Name: M R de la F Date: June 2, 1971
Age: 37 Sex: Female
Weight: 65 kg Height: 1.71 m
Profession: home
Previous history: The patient tells us that she underwent oophorectomy and mastectomy of the right breast because of an epidermoid carcinoma and metastasis. Since the time of the operation the wound has not healed properly: there is a purulent secretion, pain, and in the place of the scar there is a hazelnut-sized tumor.
Treatment: We administered 14 sessions of Donatian therapy, starting on July 1, 1971. At the end of three months treatment, the patient was released, cured.
The patient lived for eight years, after which she died of a metastasis to the lung for which she did not come to us but was treated at another clinic.
Case History # 21 Ewing’s sarcoma
Name: M G P Date: August 18, 1970
Age: 3 Sex: Female
Weight: 18 kg Height: 1.09 m
Previous history: The patient’s mother tells us that the girl had, two months ago, what appeared to be a Colles’ fracture of the left wrist. The first physician that they consulted put the left forearm in a cast, but as time went on the girl did not get better and the wrist continued to be swollen.
The parents consulted another physician who performed a biopsy of the radius of the left forearm. The result was: Ewing’s Sarcoma.
Since then, the destruction of the bone has become more aggressive; x-rays show the extension of the neoplasia, with metastases to the larger bones. The girl was given up on and the parents came to us.
Symptoms: Loss of 4 kg of weight, as well as the other symptoms mentioned: pain, edema of the left wrist, slight fever.
Physical Exploration: BP: 80/40 Pulse: 90/min Temp: 37°C
Hard, painful lymph nodes are palpated in both submaxillary regions; they are the size of grapes. The supraclavicular nodes are also swollen, as are those of the neck.
The area of the elbow has three small, hard painful lymph nodes; the wrist is swollen, and deformed in varus and adduction, with intermediate pronation. There is very intense pain upon palpation.
Diagnosis: Ewing’s Sarcoma
Treatment: We administered 17 sessions of Donatian therapy, over a period of months. On February 12, 1971, x-rays were taken of the patient’s whole skeleton, All of the bones were normal, The patient was released, cured.
Evolution of Treatment: The first treatment was on August 18, 1970. The result of the first treatment was that the pain and edema diminished, the patient’s appetite improved, the fever began to come down. Upon physical exploration the submaxillary lymph nodes seemed to be less painful and the right one was smaller than the left; the supraclavicular nodes were reduced to the size of pin-heads; the lymph nodes of the elbow were not as painful, and their size and consistency were reduced.
After the fourth treatment the pain was intermittent and slight; the edema has completely disappeared and the left forearm and wrist returned to their normal anatomical positions. Upon palpation intense pain is no longer present, and the retroinaxillary lymph nodes are reduced to the size of lentils. The supraclavicular nodes are also smaller, but the right one is smaller than the left; the fever has not returned; the lymph nodes of the elbow do not hurt and are reduced in size and consistency. X-rays of the forearm showed a possible neoformation but not a Ewing’s sarcoma.
After the eighth session, the intense pain in the left had disappeared completely; the retromaxillary lymph nodes were no longer painful and the right one disappeared; the left one was the size of a pin””head. The supraclavicular nodes disappeared as did those of the elbow. Another x-ray of the left forearm and hand was ordered which showed a marked improvement of the lesion over previous x-rays.
After the twelfth session, the girl showed no problems with her left wrist or forearm. The five final treatments were administered and x-rays taken of the patient’s entire skeleton and she was released, totally cured.
After eight years, the case is still totally cured.
Case History # 22 Metastasis of adenocarcinoma of the gall bladder
Name: E H A Date: June 8, 1964
Age: 55 Sex: Female
Weight: 69.85 kg Height: 1.66 m
Profession: businesswoman
Previous history: One year ago the patient began to feel pain in the epigastrium, near the liver, accompanied by a sensation of distention and very intense nausea. Seven months later she became icteric all over her body. On April 10, 1964 a cholecystectomy was performed. A biopsy was done with the sample removed and the result was a semi-differentiated infiltrating adenocarcinoma of the gall bladder. Cholelithiasis.
After the operation total icterus continued. The intense pain persisted. Exhaustion is more marked now than before the cholecystectomy; there is also a continuous fever of 38°C and edema of both legs. Besides the nausea, vomiting has appeared.
Physical Exploration: BP: 90/40
Painful and intensely jaundiced appearance; the patient looks cachectic, makes an enormous effort to take a step.
The abdomen is convex with a scar approximately 30 cm long that goes from the epigastrium, almost parallel to the right costal edge, to the anterior superior illiac spine where there is a tube for drainage that is releasing a yellow sanguinolent liquid. Extraction of the drainage tube does not produce pain. The epigastrium and right flank are very elevated.
There Is hepatomegalia and splenomegalia, very much gas in the abdomen and edema in both legs. The bilirubin is at a level of 1.75 mg/100 ml, alkaline phosphatase is at 1200 lU/liter, and cholesterol at 329 mg/100 ml.
Diagnosis: Metastasis of the semi-differentiated infiltrating adenocarcinoma of the gall bladder.
Treatment: We administered 5 sessions of Donatian therapy, one every three days. Twenty-one days later the patient weighed 55 kg, icterus had disappeared, bilirubin was at 3 mg/100 ml and alkaline phosphatase was at 105 IU/ml.
The patient is cured, according to clinical and laboratory examinations.
Case History # 23 Epidermoid carcinoma of the cervix. Trichomoniasis.
Name: C B M Date: June 4, 1964
Age: 32 Sex: Female
Weight: 51 kg Height: 1.57 in
Profession: businesswoman
Previous history: Leukorrhea, since more than a year ago, that is very fetid and sometimes there is a sanguinolent secretion. Bleeding during coitus. Has had 3 hemorrhages in the last three months. Alarmed, the patient consulted a gynecologist, who ordered a Pap test.
The result was a Stage IV epidermoid carcinoma of the cervix. Trichomoniasis. The gynecologist sent her to an oncologist who gave her 15 treatments of cobalt radiotherapy. After radiotherapy, the patient worsened. A new pain appeared in the lower part of the abdomen, there is diarrhea, vomiting, fever of 38°C, continuous vaginal bleeding.
Physical Exploration: BPs 105/75
Pale complexion, sunken eyes. The cervix is bleeding profusely from the right side where, at 6 and 9 o’clock, one can observe two areas with no mucous membrane that are a tawny red color. The uterus is swollen and reaches to 6 cm below the umbilical scar; it is hard, painful, wooden and inclined in antiversion.
Diagnosis: Epidermoid carcinoma of the cervix. Trichomoniasis.
Treatment: We administered 10 sessions of Donatian therapy. On June 22, 1964 another Pap test was performed that gave negative results for malignant cells. The patient was released, cured, on August 10, 1964. She weighed 63 kg upon release.
Case History # 24 Malignant melanoma
Name: E C R Date: May 23, 1974
Age: 44 Sex: Male
Weight: 70.6 kg Height: 1.75 m
Profession: Accountant (CPA)
Previous History: Arterial hypertension since 1966. Two and a half years ago a mole began to grow next to his left sideburn, about 2 cm from the left earlobe. The patient recalls one occasion when his barber cut the mole and it bled profusely.
Symptoms: Halitosis, meteorism. BPs 200/124, cephalea, cold feet, slight edema of the feet, nervousness.
Physical Exploration: A mole located 2 or 3 cm forward of the left ear; approximately 0.5 mm in diameter, purplish color, irregular surface, slight pain upon palpation.
Diagnosis: Malignant melanoma.
Treatment: We administered 7 sessions of Donatian therapy, one per week. The patient was examined again on August 23, 1974, and the test with the Oncodiagnosticator was negative. The patient was found to be clinically healthy.
Evolution of Treatment: The first treatment was on May 23, 1974. After the first treatment the mole was not painful to the touch and was not as purple or inflamed. Cold feet and edema disappeared; nervousness was less; cephalea disappeared; blood pressure went down.
After the fourth treatment, the mole looked like a freckle, was not painful or inflamed and its edges were more regular. Nervousness disappeared.
After the seventh and last treatment the mole disappeared completely; blood, pressure became normal; the patient was found to be clinically healthy. He was released on August 23, 1974, totally cured. We have received no news of any recurrence of symptoms.
Case History # 25 Epidermoid carcinoma
Name: A R A Date: August 16, 1974
Age: 72 Sex: Male.
Weight: 80 kg Height: 1.68 m
Profession: retired train conductor
Previous History: A spot appeared on the patient’s skin in November, 1973 and has gradually grown.
He consulted a skin specialist, who requested a biopsy to confirm his suspicion of spinocellular epidermoid carcinoma. Biopsy reported a well”” differentiated invasive epidermoid carcinoma at the right commissure of the lower lip.
Physical Exploration: BP: 148/68
On the right side of the lower lip, near the commissure, there is a small, bean-sized tumor. It is slightly purple, with an irregular surface and showing pain upon palpation.
Diagnosis: Well-differentiated invasive epidermoid carcinoma, at the right commissure of the lower lip.
Treatment: We administered 12 sessions of Donatian therapy, one per week. The patient was examined on November 18, 1974 and found to be clinically healthy. The test with the Oncodiagnosticator was also negative.
Evolution of Treatment: The first treatment was on August 16, 1974.
The results of the first treatment were that the tumor was not so painful upon palpation and was slightly smaller; the consistency was the same and the color was a dark brown; the edges and surface were the same.
After the fourth treatment the tumor does not hurt, inflammation is markedly reduced and the color changed to a light brown; the edges are only irregular inside the labial commissure.
After the eighth treatment the tumor is the size of a lentil and there is no pain; inflammation is very slight and the color is a pale brown.
After the twelfth treatment no tumor can be palpated and the patient’s lip is normal. He complains of no discomfort or pain. Another biopsy is done and no malignant cells are reported. He was released on November 28, 1974, totally cured. More recently the patient has communicated with us, and reports that he has had no recurrence of symptoms.