Dr. Weeks’ Comment: MS patients suffer terribly and conventional medication offers so little. Yet natural medicine offers so much! Apitherapy is painful but well accepted in the MS community but now we learn about SOUL – a drink made from crushed seeds – all organic an non-GMO – with natural flavors like passion fruit and pomegranate juice – D ribose ( a 5 carbon sugar which lowers blood sugar and gives energy and mood elevation) and whose anti-inflammatory ingredients are well proven to address illnesses like MS (see article below). Even better the first box (2 weeks trial) is offered with a full money back guarantee – so MS patients are choosing SOUL . Give it a try – RISK FREE – call SAFALAB.
Amelioration of chronic relapsing experimental autoimmune encephalomyelitis (cr-eae) using thymoquinone – biomed 2009.
Abstract
Axonal damage, demylination and inflammation of the central nervous system are the major pathological features of the human multiple sclerosis(MS). MS is thought to be due to abnormal T cell mediated immune response. Oxidative stress plays an important role in the advancement of MS. The management of oxidative stress by outlining central role of reduced glutathione. In our experiment we used Experimental autoimmune encephalomyelitis (EAE) animal model that mimic human MS and tested the effect of Thymoquinone (TQ), an oil constituent of Nigella Sativa also known as black seed. Thirty female mice of strain C57BL/6J and aged between 6 to 12 weeks were placed into 3 groups of 10 and were given Myelin Oligodendrocyte Glycoprotein (MOG) subcutaneously (SC) to induce EAE. Group A was the control group. Group B received MOG (SC) and TQ intraperiotoneally (IP) from day 1 till day 50. Group C received MOG (SC) and TQ (IP) on the appearance of first sign and symptoms of chronic relapsing EAE (CR-EAE). All Mice were examined daily for behavioral deficits and all euthanized and sacrificed on day 50. Preliminary result showed that TQ due to its antioxidant effect is almost 90% preventive and 50% curative in CR-EAE. This result could assist further studies on the mechanism of action of TQ in CR-EAE and explore the possibility of treating the human chronic relapsing multiple sclerosis phase.