Hashimoto’s Thyroiditis and Seeds

Dr Weeks’ Comment: Anytime you read “its” in a diagnostic term like “arthritis” or “uveitis” or “epicondylitis” or “colitis” it means “inflammation” and black cumin seed is a cornerstone of Dr. Weeks’ “anti-inflammatory diet”. Here we see how seed nutrition helps people with anti-immune Hashimoto’s thyroiditis.

The Effects of Powdered Black Cumin Seeds on Markers of Oxidative Stress, Intracellular Adhesion Molecule (ICAM)-1 and Vascular Cell Adhesion Molecule (VCAM)-1 in Patients With Hashimoto’s Thyroiditis

Mahdieh Abbasalizad Farhangi et al 

Clin Nutr ESPEN. 2020 Jun;37:207-212. doi: 10.1016/j.

Abstract

Oxidative stress plays an important role in the pathogenesis of Hashimoto’s thyroiditis. Because of the major anti-oxidant properties of black cumin, the current study aimed to evaluate the effect of powdered Nigella sativa seeds on markers of oxidative stress, endothelial dysfunction and serum lipids in patients with Hashimoto’s thyroiditis.

Conclusions: Giving attention to the potent beneficial effects of powdered black cumin seeds in improving oxidative stress, endothelial dysfunction, serum lipids and anthropometric features in patients with Hashimoto’s thyroiditis, this medicinal plant can be considered as a therapeutic agent in management of Hashimoto-related metabolic abnormalities.

The Effects of Nigella Sativa on Thyroid Function, Serum Vascular Endothelial Growth Factor (VEGF) – 1, Nesfatin-1 and Anthropometric Features in Patients With Hashimoto’s Thyroiditis: A Randomized Controlled Trial

Mahdieh Abbasalizad Farhangi et al 

BMC Complement Altern Med  . 2016 Nov 16;16(1):471

Abstract

Background: Hashimoto’s thyroiditis is an autoimmune disorder and the most common cause of hypothyroidism. The use of Nigella sativa, a potent herbal medicine, continues to increase worldwide as an alternative treatment of several chronic diseases including hyperlipidemia, hypertension and type 2 diabetes mellitus (T2DM). The aim of the current study was to evaluate the effects of Nigella sativa on thyroid function, serum Vascular Endothelial Growth Factor (VEGF) – 1, Nesfatin-1 and anthropometric features in patients with Hashimoto’s thyroiditis.

Conclusions: Our data showed a potent beneficial effect of powdered Nigella sativa in improving thyroid status and anthropometric variables in patients with Hashimoto’s thyroiditis. Moreover, Nigella sativa significantly reduced serum VEGF concentrations in these patients. Considering observed health- promoting effect of this medicinal plant in ameliorating the disease severity, it can be regarded as a useful therapeutic approach in management of Hashimoto’s thyroiditis.

Powdered Black Cumin Seeds Strongly Improves Serum Lipids, Atherogenic Index of Plasma and Modulates Anthropometric Features in Patients With Hashimoto’s Thyroiditis

Mahdieh Abbasalizad Farhangi et al 

Lipids Health Dis  2018 Mar 27;17(1):59. 

Background: Hashimoto’s thyroiditis is associated with serious alterations in serum lipids and glucose homeostasis. The aims of the current study were to evaluate the effect of powdered Nigella sativa on serum lipids, glucose homeostasis and anthropometric variables in patients with Hashimoto’s thyroiditis.

Conclusions: Giving attention to the potent beneficial effects of powdered black cumin seeds in improving serum lipid profile and anthropometric features in patients with Hashimoto’s thyroiditis, this medicinal plant could be considered as a beneficial herbal supplement alongside with the disease- specific medications including Levothyroxine in management of Hashimoto’s thyroiditis- related metabolic abnormalities.

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