Dr. Weeks Comment: With autism epidemic growing from 1 in 10,000 kids in 1985 to 1 in 44 kids now and projected to be 1 in 2 kids in 2032, it is past time to understand this fact: Autism is an inflammatory disorder. (read the links below!) That means inflammation makes the autistic person suffer more and have less control of symptoms. That means Anti-inflammatory agents are MANDATORY but not the dangerous over the counter NSAIDs (Tylenol™, Motrin™, Ibuprofen™ etc because those are toxic if taken in excess (they have a “narrow therapeutic window” meaning some is good but too much is toxic). The references below begin to convince you of the link between inflammation and autism. (by the way, same with Alzheimer’s – read THIS and THIS) What are the safest and most effective anti-inflammatory agents? Cold pressed, organic non-GMO anti-inflammatory seeds – the treasure chest of nature (seed naturally concentrate nutrients 20x more than the flesh of the fruit of vegetable). Eat the seed and see the results this loving father of an autistic son saw after which he reported that NOTHING has helped his son as much as seed nutrition – organic and non-GM).
https://www.ncbi.nlm.nih.gov/pubmed/16401547
Cerebrospinal fluid and serum markers of inflammation in autism, Zimmerman et al., 2005
https://www.ncbi.nlm.nih.gov/pubmed/16139734
Elevation of tumor necrosis factor-alpha in cerebrospinal fluid of autistic children.[/url], Chez et al., 2007
(TNF-alpha is a marker of inflammation)
https://www.ncbi.nlm.nih.gov/pubmed/17560496
Microglial activation and increased microglial density observed in the dorsolateral prefrontal cortex in autism., Morgan et al., 2010, 2012
(microglial activation = inflammation)
https://www.ncbi.nlm.nih.gov/pubmed/20674603
Microglia in the cerebral cortex in autism., Tetreault et al., 2012
https://www.ncbi.nlm.nih.gov/pubmed/22466688
Brain Inflammation A Hallmark Of Autism, Large-Scale Analysis Shows, Johns Hopkins Medicine, 2014
https://www.hopkinsmedicine.org/news/media/releases/brain_inflammation_a_hallmark_of_autism_large_scale_analysis_shows
Focal brain inflammation and autism, Theoharides, 2013
https://jneuroinflammation.biomedcentral.com/articles/10.1186/1742-2094-10-46
Relevance of Neuroinflammation and Encephalitis in Autism, Kern, 2015
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717322
From molecules to neural morphology: understanding neuroinflammation in autism spectrum condition, Young, Molecular Autism, 2016
https://molecularautism.biomedcentral.com/articles/10.1186/s13229-016-0068-x
Evidence of oxidative damage and inflammation associated with low glutathione redox status in the autism brain, 2012
https://www.nature.com/articles/tp201261
Evidence linking oxidative stress, mitochondrial dysfunction, and inflammation in the brain of individuals with autism, 2014
https://www.frontiersin.org/articles/10.3389/fphys.2014.00150/full
Schizophrenia and autism: both shared and disorder-specific pathogenesis via perinatal inflammation, 2011
https://www.nature.com/articles/pr9201190
Immune involvement in schizophrenia and autism: etiology, pathology and animal models, 2009
https://www.sciencedirect.com/science/article/pii/S0166432808006980
Neuro-inflammation, blood-brain barrier, seizures and autism, 2011
https://jneuroinflammation.biomedcentral.com/articles/10.1186/1742-2094-8-168