Fibroblasts feed Cancer

Dr. Weeks’ Comment:  To clarify why Corrective Cancer Care includes anti-oxidants such as NAC,  Glutathione Metformin and other “centisible” remedies  watch this very interesting and provocative YouTube video sent to me by Jonathan Schoch:

http://www.youtube.com/watch?v=ssoAou8Ll6w

Check out this Take Home Message:   “So, we can treat cancer with cheap drugs that you can buy either in the super market or with things you can get from a family doctor.”  (listen to YouTube  from 22:30 – 22:50)

NOTES from my listening to this YouTube lecture and Q&A session:

Title: “Parasitic Metabolic Coupling in Cancer: Understanding Oxidative Stress and Autophagy in the Tumor Microenvironment.”

Experimental Evidence Suggests

Connective tissue breaks down from oxidation and feeds the cancer cells

which, in turn, secrete h2O2 in fibroblasts to get more food

Autophagy provides:

1) nutrients for the cancer

2) ROS mutates cancer cells to aid their avoidance of chemo and radiation

3) protection against apoptosis

 

AND

Otto Warburg was half right

cancer is glycolytic

fibroblasts are oxidative

But once these cells mix together – they reverse roles

cancer cells thrive on mitochondrial fuel lactate and ketones

 

AND

Cancer cells and oxidative stress

– cancer cells upregulate own antioxidants perioxiredoxin while benefiting from fibroblasts being oxidized and leading to autophagy.

 

AND

Caveolin enzyme disappears – this is bad

as it is a trigger for more oxidative stress and

NAC  preserves Caveolin (kills cancer)

Metformin (anti-complex 1 inhibitor) preserves Caveolin which kills cancer

Choloquin preserves Caveolin which kills cancer

 

Treatment Strategy

NAC blocks the ROS which fuels cancer by spreading autophagy

of fibroblasts in the nest of connective tissue which protects the developing cancer cells.

 

DNA damage

– mostly in Connective tissue (most mutations take place in stroma)

block with NAC

block with NO inhibitor

Rx antioxidants

Rx  Metformin is anticancer since it is a mitochondrial poison

15 studies    25-75% reduction all types of cancers in  (listen to youtube 19:40 -20:20)

 

 

Avoid lactate and ketones

– metastatic disease is  10X more with ketones and lactate

WARNING: the standard of care is for oncologists to give IV lactate ringers (causing metastasis  (listen to youtube video at 13:07)  SO, don’t allow your doctor to give you IV lactated ringer solution (cancer love lactate and it encourages metastases!)

 

 

 

Take Home Message:

 

“So we can treat cancer with cheap drugs that you can buy either in the super market or with things you can get from a family doctor.”

(listen to youtube  from 22:30 – 22:50)

 

 

 

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