Self Disseminating Vaccines

Dr. Weeks’ Comment: Where was the fully informed consent?

Expert Rev Vaccines. 2016 Jan 2; 15(1): 31–39.Published online 2015 Nov 2. doi: 10.1586/14760584.2016.1106942PMCID: PMC4732410PMID: 26524478

Self-disseminating vaccines for emerging infectious diseases

Aisling A. Murphy, a Alec J. Redwood, b and Michael A. Jarvis * , a


Modern human activity fueled by economic development is profoundly altering our relationship with microorganisms. This altered interaction with microbes is believed to be the major driving force behind the increased rate of emerging infectious diseases from animals. The spate of recent infectious disease outbreaks, including Ebola virus disease and Middle East respiratory syndrome, emphasize the need for development of new innovative tools to manage these emerging diseases. Disseminating vaccines are one such novel approach to potentially interrupt animal to human (zoonotic) transmission of these pathogens.

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