Dr. Weeks’ Comment: Life is miraculous. Just a brief contemplation of how things are happening around us should drop us to our knees in astonishment. Now we learn of a life form, a tiny jellyfish, which has a very remarkable response to threat. What it does is it reverts to a juvenile version of itself. I am sure scientists will be studying the biochemistry behind this because even magicians leave hints so this may become a new Anti Aging modality for us. What we know to be true is that life is orchestrated by biochemistry so there is a lot to learn here about “cellular transdifferentiation”. But I wonder, how would you like a “do over” in response to stress and find yourself back in diapers?
“Immortality is generally considered the realm of the gods or science fiction, a fantasy that’s actively pursued by tech entrepreneurs in macabre experiments that include injecting “young blood”, cryopreservation, or resurrection in an AI afterlife.
But one ethereal, thimble-shaped jellyfish has already cracked the code.
As associate professor Maria Pia Miglietta, a marine biologist at A&M University in Texas, explains, Turritopsis dohrnii has an incredible ability to cheat death.
“Turritopsis is unique, because when faced with unfavourable conditions – and I mean high temperature, physical cutting, starvation, chemicals in the water, you name it – when you try to kill the jellyfish, it doesn’t die.”
Most normal jellyfish start off life as larvae. They metamorphose into polyps (tiny, stationary soft bodies) that bud off swimming medusas, which grow up to become adult jellies. Eventually, after reproducing, most will stop swimming, crumble a little and then die.
But the immortal jellyfish escapes that fate. It reverts to a juvenile form, and starts its life cycle again.
The process is called “cellular transdifferentiation”, Miglietta says. The jellyfish looks like it’s dying and sinks to the bottom. Then – like a butterfly returning to a caterpillar – it shrinks into a ball, and within 24 to 48 hours, buds off a new polyp with the same identical genome, she says.
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It’s one of “nature’s coolest tricks”, says Guardian reader Raquel López-Aragón. “When this jellyfish gets old or gets hurt, instead of just dying like most animals, it transforms itself back into a baby jellyfish and grows up all over again. It can do this as many times as it wants, which means theoretically it never has to die from getting old, it just keeps hitting the reset button on its life.”
In the lab, where Miglietta studies them, these jellies can theoretically live for ever. However, for some in the wild, getting eaten may eventually end that dream run.
Globally, there are eight accepted species of Turritopsis – but (so far) only one holds the key to eternal life.
Immortal jellyfish are only a few millimetres in size. But, if you know what to look for, they can be found in many places, from the Mediterranean sea, to the Atlantic, from the coast of Japan to Panama and Brazil.
As another reader remarks, the immortal jellyfish does “exactly what it says on the tin”. “They have the very enviable ability to simply turn back into a juvenile at any sign of stress, which is something that I’m sure we all wish extended to humans.”
With their delicate bodies and veil of tentacles, Dr Lisa-ann Gershwin, a biologist specialising in jellyfish, describes Turritopsis as “exquisite” and “the most beautiful little creature”. But what makes them remarkable is their capacity for reincarnation.
Since ancient times, humans have speculated about eternal life, she says, it’s one of the things that unites us all.
“It’s so hardwired in humans to not want to die. And I think the drive that we have to survive, and the absurdity of that being in a jellyfish – the juxtaposition of those two just entertains me to no end.”
SOURCE: https://www.theguardian.com/environment/2026/aug/04/when-you-kill-it-it-doesnt-die-the-jellyfish-that-has-cracked-the-secret-of-immortality?utm_campaign=august5morningnote&utm_medium=email&utm_source=iterable&utm_content=morningnote