March 10th2020
The Immune Enhancement 12 Pak
My friends, here is what you need to know about enhancing your immune system in 2020. Why are respiratory viral and retroviral infections dangerous? They are dangerous because they defeat your immune system, incite inflammation, deplete your essential nutrients and attack your ability to breathe and transfer oxygen.
The father of homeopathy, Dr. Samuel Hahnemann, taught that all symptoms are in fact healing gestures. How’s that? All symptoms are efforts to fight the stressor which causes the dis-ease which in turn manifests as illness resulting in disability or death. Our tried and proven therapeutic strategy is to give the “Healer Within” all the tools it needs to survive and thrive. It is that simple. Remember what the father of modern medicine William Osler (1849- 1919) proclaimed: “One of the first duties of the physician is to educate the masses not to take medicines”. Why would a wise doctor teach that??? Well, that is wise because prescription, pharmaceutical, patented, expensive, synthetic, foreign to the human body i.e.”alien” drugs don’t heal. What do they do? These drugs simply poison enzyme systems and buy time suppressing symptoms (not a bad thing!) so that the Healer Within can rally and gather all the resources it needs to overcome the infectious agent. Food and nutrients heal. Drugs typically simply suppress symptoms. Not a bad start, but better to correct your imbalances: increase what you are deficient in and detoxify that which you have too much of. Simple. Ancient. Wise Advice.
It is the same with any life threatening infection which challenges your Healer Within. So, in order to optimize your odds of surviving and thriving, if you simply supply your Healer Within all the ammunition it needs, it will protect you optimally. After all, we are fearfully and wonderfully made!
What are those nutrients which are the ammunition you need to survive and thrive?
Here are the Immune Enhancement 12 Pak items which many people bet their lives on.
1) SOUL – anti-inflammatory nutrient dense organic, non -GMO seed drink; (seed oils actively transport oxygen)
2) CORE – organic specific nutrient dense detoxifying organic, non-GMO seed drink;
3) AntiOxidant™ Assist- Vitamin C antioxidant and cellular protector;
4) Dr. Detox™ – cellular detoxifier and chelator of toxic viri and heavy metals;
5) Turb-O2™ – stabilized molecular oxygen to enhance blood oxygen carrying capacity;
6) Melatonin – water and fat soluble anti-oxidant and anti-viral’
7) Acetylglutathione – lung resilience (superior to NAC aka N-acetylcysteine);
8) Light Assist™ – Vit D3 is active pro-hormone for immune enhancement;
9) Selenium – powerful anti-viral mineral
10) Iodine – powerful anti-pathogen element;
11) Zinc – membrane protector and anti-viral agent and potentiator of anti-viral drugs;
12) A-25 (Vitamin A palmitate) 25,000 IU/capsule – powerful safe and effective anti-viral agent)
The Scientific and Clinical Rationale
for SAFALAB’s Immune Enhancement 12 Pak Remedies
1- SOUL
This is a super natural drink made from organic, non-GMO whole crushed cold pressed anti-inflammatory seeds: black cumin, raspberry and Chardonnay grape) which deliver three benefits better than anything else on the market to my knowledge: 1) nutrient density 2) oxygenation of cells 3) telomere protection with resulting anti-aging.
SUMMARY CUT SHEET
https://myrainoffice.com/document_library/third party cell assay CS.pdf
2- CORE
This is a powerful detoxifying alkalinizing drink made from organic, non-GMO whole crushed cold pressed detoxifying seeds (milk thistle, cranberry and black cumin) with 6 powerful concentrated greens (spirulina, chlorophyllin, kale, dandelion, aloe vera and wheat grass) which create organ specific (liver, gall bladder, pancreas, intestinal, kidney, bladder, prostate) well as systemic detoxification.
SUMMARY CUT SHEET
https://myrainoffice.com/document_library/core-cutsheet%5B1%5D.pdf
3 – IODINE/IODIDE
Iodine, at appropriate dosages, kills all pathogens which infect the human body: viruses, bacteria, molds, fungi, yeasts and protozoa. Commonly used as a topical or aerosolized antiseptic, it is far more valuable than simply a disinfectant as it kills pathogens in seconds. Benefits for iodine, in addition to killing pathogens, include optimization of lung function, treatment of tuberculosis,(1) optimization of thyroid function, reducing risk of breast cancer and other cancers as well as general immune optimization. Side effects? It takes high doses over a long period of time to create thyroid dysregulation, metallic taste in mouth, sore gums and diarrhea. In over 30 years of prescribing iodine, I have never seen any side-effects so I consider it safe and effective.
RESEARCH ARTICLE
Mechanisms of the action of povidone-iodine against human and avian influenza A viruses: its effects on hemagglutination and sialidase activities
Author: Nongluk Sriwilaijaroen, et al
Virology Journal volume 6, Article number: 124 (2009) Cite this article
Source https://virologyj.biomedcentral.com/articles/10.1186/1743-422X-6-124
Background
Influenza virus infection causes significant morbidity and mortality and has marked social and economic impacts throughout the world. The influenza surface glycoproteins, hemagglutinin (HA) and neuraminidase (NA), act cooperatively to support efficient influenza A virus replication and provide the most important targets for anti-influenza chemotherapy. In this study, povidone-iodine (PVP-I), which has a broad-spectrum microbicidal property, was examined for its inhibitory effects against influenza virus infection in MDCK cells and the mechanisms of PVP-I action on HA and NA were revealed.
Results
Results obtained using a novel fluorescence- and chromogenic-based plaque inhibition assay showed that 1.56 mg/ml PVP-I inhibited infections in MDCK cells of human (8 strains) and avian (5 strains) influenza A viruses, including H1N1, H3N2, H5N3 and H9N2, from 23.0–97.5%. A sialidase inhibition assay revealed that PVP-I inhibited N1, N2 and N3 neuraminidases with IC50 values of 9.5–212.1 μg/ml by a mixed-type inhibition mechanism. Receptor binding inhibition and hemagglutinin inhibition assays indicated that PVP-I affected viral hemagglutinin rather than host-specific sialic acid receptors.
Conclusion
Our study confirms the inhibition of avian and human influenza A virus infection by PVP-I and demonstrates that PVP-I inhibits both viral HA binding activity and viral NA catalytic hydrolysis, mediating virus entry into host cells, and virion release and spread to a new host cell, respectively. Thus, PVP-I, for which there has been no report of resistance, is a potential agent that not only prevents viral infections but also reduces the spread of influenza viruses in epidemic and pandemic areas.
4- SELENIUM
Professor Harry Foster, a dear departed friend and pioneering medical geographer, taught that selenium was essential for eradicating HIV, another nasty virus (actually, a retrovirus). That is accurate because selenium is a potent anti-viral mineral. Selenium facilitates enzymatic processes which enhance immune response to viral infections. Side effects? Serious selenium toxicity includes visual disturbances at high doses but have never been reported to have caused any fatalities.
RESEARCH ARTICLE
Dietary selenium in adjuvant therapy of viral and bacterial infections.
Steinbrenner H et al
Adv Nutr. 2015 Jan 15;6(1):73-82. doi: 10.3945/an.114.007575. Print 2015 Jan.Abstract
Viral and bacterial infections are often associated with deficiencies in macronutrients and micronutrients, including the essential trace element selenium. In selenium deficiency, benign strains of Coxsackie and influenza viruses can mutate to highly pathogenic strains. Dietary supplementation to provide adequate or supranutritional selenium supply has been proposed to confer health benefits for patients suffering from some viral diseases, most notably with respect to HIV and influenza A virus (IAV) infections. In addition, selenium-containing multimicronutrient supplements improved several clinical and lifestyle variables in patients coinfected with HIV and Mycobacterium tuberculosis. Selenium status may affect the function of cells of both adaptive and innate immunity. Supranutritional selenium promotes proliferation and favors differentiation of naive CD4-positive T lymphocytes toward T helper 1 cells, thus supporting the acute cellular immune response, whereas excessive activation of the immune system and ensuing host tissue damage are counteracted through directing macrophages toward the M2 phenotype. This review provides an up-to-date overview on selenium in infectious diseases caused by viruses (e.g., HIV, IAV, hepatitis C virus, poliovirus, West Nile virus) and bacteria (e.g., M. tuberculosis, Helicobacter pylori). Data from epidemiologic studies and intervention trials, with selenium alone or in combination with other micronutrients, and animal experiments are discussed against the background of dietary selenium requirements to alter immune functions.
5- MELATONIN
Melatonin is NOT just for helping enhance sleep and it is NOT an hypnotic (sleep inducing sedative) rather it functions to synchronize your neuro-endocrine system and endogenous circadian clock to what is happening around you. For that reason, melatonin is also a great remedy to help the groggy person feel wide awake and chipper – ready to go – when taken in the morning! But in addition to synchronizing you to the world around you and enhancing your immune system to protect against environmental stressors, melatonin is also a powerful anti-viral agent. Being both a fat soluble and water soluble anti-oxidant, melatonin is high dose is worthy of an honored place in your first aid home kit.
RESEARCH ARTICLE
This peer reviewed scientific articleis just one of many which demonstrates the anti-viral benefits of melatonin
Melatonin possesses an anti-influenza potential through its immune modulatory effect
Shing-HwaHuangabcET AL
Abstract
Melatonin is 1) anti viral 2) anti oxidant 3) immune enhancing and 4) synergetic with other anti-viral agents
Influenza is an infectious disease caused by an RNA virus that affects birds and mammals. It is a leading cause of morbidity, mortality and economic loss worldwide. Under influenza A virus infection, an uncontrolled inflammatory response in the lungs frequently leads to severe pneumonia. The anti-inflammatory and immune modulatory effects of melatonin may provide a beneficial effect for this disease. In this study, we found that melatonin treatment significantly decreases the expression of TNF-α, IL-6 and IFN-γ, and increases the production of IL-10 and TGF-β. The induction of IL-10 by melatonin occurs via the up-regulation of IL-27 expression in dendritic cells. Melatonin also significantly inhibits the production of TNF-α in CD8 T cells. Co-treatment of melatonin and ribavirin significantly increases the survival of virus-infected mice compared to ribavirin alone. Our study suggests that melatonin possesses a therapeutic potential in influenza-induced pneumonia as an adjuvant treatment with anti-viral drugs.
Conclusion
This study is the first to demonstrate the therapeutic potential of melatonin in severe influenza A H1N1 virus infections. Our results indicated that high-dosemelatonin treatment significantly increased the survival of influenza A virus-infected Balb/c mice. Melatonin treatment protects mice from influenza A virusinduced mortality through its anti-inflammatory and immune modulatory effects. Furthermore, melatonin also exhibited a synergistic effect with an anti-viral drug. Our study provides the theoretical basis for future applications of melatonin in the treatment of influenza A virus infection.
AND
a small section of an article: by Dr Jill Carnahan
Melatonin and the Viral Infections
Melatonin is a well known biological agent that influences many bodily functions. Melatonin is best known for its role in circadian rhythms and is used as a popular sleep aid. But research is finding that melatonin may have far more widespread applications.
Melatonin has been found to inhibit the action of an inflammasome known as NLRP3 – one of the primary inflammasomes involved in the exaggerated immune response seen in critical viral infection cases.
Melatonin’s ability to suppress the activation of NLRP3 has been found to:
- Counteract severe inflammatory responses
- Lower production of proinflammatory cytokines
- Lower infiltration of immune cells into lungs
- Reduce lung tissue injury
Melatonin’s role in suppressing the inflammatory response is likely one of the reasons children under the age of 9 rarely present with severe symptoms when infected with a virus. This is because young children can have up to 10 times the peak melatonin levels of older adults.
AND
Here is an impressive study. “Melatonin, nitric oxide and ascorbic acid can reduce viral virulence by inhibiting NLRP3 inflammasomes to stop the perpetuation of cytokine storms.“
EXCERPT
“It is now clear as crystal why authorities and medical experts, scientists around the world are deeply concerned over the spread of COVID-19. SARS-CoV-2 is a coronavirus that uses the same deadly mechanisms as SARS-CoV to activate NLRP3 inflammasomes to initiate cytokine storms that can result in fatal acute respiratory distress syndrome and acute lung injury (ARDS/ALI).
SARS-CoV-2 may also be 1,000 times more infectious and virulent than SAR-CoV due to the furin cleavage site [57], which basically allows this coronavirus to be activated anywhere in host tissues and organs. Activation of SARS-CoV-2 allows it bind effectively to ACE2, causing more damage and destruction in the vital cardiovascular system and other critical pathways involving angiotensin-converting enzyme 2.
One important aspect that has not been elucidated is the importance of ACE2 in the progression of ARDS. Melatonin, nitric oxide and ascorbic acid (vitamin C) are all inextricably intertwined and deeply involved with ACE2. Melatonin, nitric oxide and ascorbic acid can reduce COVID-19 virulence by inhibiting NLRP3 inflammasomes to stop the perpetuation of cytokine storms. Their critical roles in biochemical reactions and biological pathways that involve ACE2 must be fully explored as part of our fight against COVID-19.”
6- VITAMIN C
Vitamin C is a safe and powerful anti-viral agent. In acute situations we endorse intravenous treatments of up to 100 grams a day but,for oral usage, 1 gram three times a day is sufficient for anti-viral benefits.
RESEARCH ARTICLE
Vitamin C Is an Essential Factor on the Anti-viral Immune Responses through the Production of Interferon-α/β at the Initial Stage of Influenza A Virus (H3N2) Infection.
Kim Y1, et al
Immune Netw. 2013 Apr;13(2):70-4. doi: 10.4110/in.2013.13.2.70. Epub 2013 Apr 30.
L-ascorbic acid (vitamin C) is one of the well-known anti-viral agents, especially to influenza virus. Since the in vivo anti-viral effect is still controversial, we investigated whether vitamin C could regulate influenza virus infection in vivo by using Gulo (-/-) mice, which cannot synthesize vitamin C like humans. First, we found that vitamin C-insufficient Gulo (-/-) mice expired within 1 week after intranasal inoculation of influenza virus (H3N2/Hongkong). Viral titers in the lung of vitamin C-insufficient Gulo (-/-) mice were definitely increased but production of anti-viral cytokine, interferon (IFN)-α/β, was decreased. On the contrary, the infiltration of inflammatory cells into the lung and production of pro-inflammatory cytokines, tumor necrosis factor (TNF)-α and interleukin (IL)-α/β, were increased in the lung. Taken together, vitamin C shows in vivo anti-viral immune responses at the early time of infection, especially against influenza virus, through increased production of IFN-α/β.
7- VITAMIN D3
Vitamin D3 is an essential pro-hormone which can help you survive the Coronavirus. Studies show that taking vitamin D3 – the active form of vitamin D results in less severe respiratory infections and also required less antibiotic use.
Is vitamin D3 safe in high doses? The science resoundingly says “Yes”.
RESEARCH ARTICLE
This 2011 study in Critical Care journal by Dr. Amrein et al is encouraging: “Short-term effects of high-dose oral vitamin D3 in critically ill vitamin D deficient patients: a randomized, double-blind, placebo-controlled pilot study.”
INTRODUCTION:
Vitamin D deficiency is encountered frequently in critically ill patients and might be harmful. Current nutrition guidelines recommend very low vitamin D doses. The objective of this trial was to evaluate the safety and efficacy of a single oral high-dose vitamin D3 supplementation in an intensive care setting over a one-week observation period.
CONCLUSIONS:
This pilot study shows that a single oral ultra-high dose of cholecalciferol corrects vitamin D deficiency within 2 days in most patients without causing adverse effects like hypercalcemia or hypercalciuria. Further research is needed to confirm our results and establish whether vitamin D supplementation can affect the clinical outcome of vitamin D deficient critically ill patients.
8- ACETYLGLUTATHIONE
Glutathione is a powerful anti-oxidant and anti-inflammatory agent which is tremendously valuable for people suffering from lung diseases and infections of the lung. The Coronavirus creates inflammation and what lowers native glutathione leading to further damage from inflammation. Once infected with the Coronavirus, you need glutathione and other sulfur rich foods like onions and garlic as well as cruciferous vegetables like broccoli, kale, cabbage. Glutathione itself is too unstable a molecule to be taken alone but if it is acetylated, then it is stable, well absorbed and highly beneficial.
RESEARCH ARTICLE
Glutathione-Capped Ag2S Nanoclusters Inhibit Coronavirus Proliferation through Blockage of Viral RNA Synthesis and Budding.
Du T1, et al
Source: ACS Appl Mater Interfaces. 2018 Feb 7;10
Development of novel antiviral reagents is of great importance for the control of virus spread. Here, Ag2S nanoclusters (NCs) were proved for the first time to possess highly efficient antiviral activity by using porcine epidemic diarrhea virus (PEDV) as a model of coronavirus. Analyses of virus titers showed that Ag2S NCs significantly suppressed the infection of PEDV by about 3 orders of magnitude at the non-cytotoxic concentration at 12 h post-infection, which was further confirmed by the expression of viral proteins. Mechanism investigations indicated that Ag2S NCs treatment inhibits the synthesis of viral negative-strand RNA and viral budding. Ag2S NCs treatment was also found to positively regulate the generation of IFN-stimulating genes (ISGs) and the expression of pro-inflammation cytokines, which might prevent PEDV infection. This study suggests the novel underlying of Ag2S NCs as a promising therapeutic drug for coronavirus.
9) ZINC
Zinc is the major element required for maintaining cell membrane integrity and repair and recovery of the molecules which maintain string barriers between you and the pathogen. Zinc is essential for lung health and anti-viral protection for all cells.
Role of zinc-finger anti-viral protein in host defense against Sindbis virus.
Kozaki T1, Takahama M2, Misawa T1, Matsuura Y3, Akira S4, Saitoh T1.
Int Immunol. 2015 Jul;27(7):357-64. doi: 10.1093/intimm/dxv010. Epub 2015 Mar 10.
Abstract
Accumulating evidence indicates that type I interferon (IFN) mediates the host protective response to RNA viruses. However, the anti-viral effector molecules involved in this response have not been fully identified. Here, we show that zinc-finger anti-viral protein (ZAP), an IFN-inducible gene, plays a critical role in the elimination of Sindbis virus (SINV) in vitro and in vivo. The loss of ZAP greatly enhances the replication of SINV but does not inhibit type I IFN production in primary mouse embryonic fibroblasts (MEFs). ZAP binds and destabilizes SINV RNA, thereby suppressing the replication of SINV. Type I IFN fails to suppress SINV replication in ZAP-deficient MEFs, whereas the ectopic expression of ZAP is sufficient to suppress the replication of SINV in MEFs lacking the expression of type I IFN and the IFN-inducible genes. ZAP-deficient mice are highly susceptible to SINV infection, although they produce sufficient amounts of type I IFN. Therefore, ZAP is an RNA-sensing anti-viral effector molecule that mediates the type-I-IFN-dependent host defense against SINV.
10) VITAMIN A PALMITATE
11) DrDETOX™
– email md@weeksmd.com for the proprietary info on DrDetox™
12) TURB-O2™
– email md@weeksmd.com for the proprietary info on Turb-O2™
SO….
WHAT TO DO TO PROTECT YOURSELF and your LOVED ONES ?
HERE IS YOUR “TAKE ACTION NOW” MESSAGE
A competent medical doctor can rescue you if you are infected with the a virus or a retrovirus using intravenous infusion (IV) ozone, IV hydrogen peroxide , IV vitamin C and IV glutathione as well as IV Agrentyn23 silver as well as other safe and effective agents.
Being well hydrated with IV 0.9% normal saline if needed, is essential as is being optimally nourished with seeds which are the most nutrient dense food on earth.
Every home should have
1) a nebulizer for H2O2 or glutathione
2) a powerful, safe far-infrared sauna such as what SAFALAB sells (ask for the discount).
But the minimum responsible protection which everyone should have stockpiled in his or her home is the Immune Enhancement 12 Pak available HERE from Safalab, Inc. for $568.