Omega-3 fatty acids and bipolar disorder: a review

^a Psychopharmacology Research Laboratory, McLean Hospital, Belmont, MA 02478, USA

^b Department of Psychiatry, Harvard Medical School, Boston, MA, USA

^c Department of Psychiatry, Baylor College of Medicine, Houston, TX, USA

^d Department of Psychiatry, Free University of Berlin, Berlin, Germany

Abstract

The important role of the omega-3 fatty acids in the pathophysiology and treatment of bipolar disorder is now supported by a substantial body of indirect and direct evidence. This paper will describe the clinical and pharmacological features of bipolar disorder, review the available data regarding omega-3 fatty acids in bipolar disorder and provide recommendations for future research.

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