Dr. Weeks’ Comment: The FDA sometimes gets things right and on those occasions, it is good to congratulate them. For example after travesties like THIS and THIS and THIS, the FDA just approved the drug Metformin for an Anti-Aging Study on Humans. Granted they are 20 years too late, but better late than never. They were also late in approving the drug for diabetes use in the USA. After being approved for diabetics to use in England in 1957, the FDA delayed allowing it into the USA for an bewildering 37 years!
Why is metformin so valuable? Well, let’s let top researcher share their enthusiasm
“Although it might seem like science fiction, researchers have already proven that the diabetes drug metformin extends the life of animals, and the Food and Drug Administration in the US has now given the go ahead for a trial to see if the same effects can be replicated in humans.”
“I have been doing research into aging for 25 years and the idea that we would be talking about a clinical trial in humans for an anti-aging drug would have been thought inconceivable…20 years ago aging was a biological mystery. Now we are starting to understand what is going on.”
“Scientists think the best candidate for an anti-aging drug is metformin, the world’s most widely used diabetes drug which costs just 10p a day. Metformin increases the number of oxygen molecules released into a cell, which appears to boost robustness and longevity.”
Dr Simon Melov of the Buck Institute for Research on Aging added:
“You’re talking about developing a therapy for a biological phenomenon which is universal and gives rise to all of these diseases. And if you’ve got a therapy for this thing, these diseases just go away.”
In addition to lowering blood sugar (itself an anti-aging benefit), metformin stimulates an important enzyme found within all of our cells called adenosine monophosphate-activated protein kinase (AMPK) This enzyme activation augments the beneficial effects of calorie restriction which scientists have proven years ago to be the most reliable method of slowing and reversing biomarkers of animal and human aging especially when paired with optimal seed nutrition and adequate daily exercise to oxygenate the blood and all tissues.
How can you get metformin? Well if you are not in Mexico where you can just buy it from the drug store clerk, you will need a prescription. But to get the benefits of metformin, you can take the natural non-prescription version: Berberine Plus and SugarAssist. As in all cases where patented prescription drugs offer a benefit, there are naturally occurring herbs, amino acid or vitamins/mineral combinations which offer the same benefits in a more ‘centsible” manner – safer, more effective and more cost effective.
|Here are some accurate quotes from worldwide news sources:
Life Extension® Has Championed Metformin for 20 Years
Life Extension Magazine® listed metformin as one of many important offshore medications way back in 1995. And now, 20 years later, even the FDA concurs that metformin has potential to delay the onset of degenerative disease.
But contrary to all the news headlines, metformin cannot enable humans to live to 120 years of age all by itself. What it may do is allow humans to age better today ”” thereby staving off degenerative disease long enough for age-reversalbreakthroughs to become clinically available.
Metformin’s primary mechanism is to enhance the activity of an enzyme found within our cells called adenosine monophosphate-activated protein kinase ”” or AMPK for short. AMPK activation helps mimic the beneficial effects of calorie restriction, the best documented method of slowing and reversing biomarkers of human aging.
Life Extension has long endorsed AMPK activation as a method of slowingbiological aging. We advocate that our supporters utilize some proven method to increase their cellular AMPK activity ”” which could add substantial healthy years to the average life span.
It is worth noting that if you’re presently taking 1,000 to 2,550 mg of metformin daily, you don’t have to do anything ”” simply enjoy this drug’s anti-aging benefits. But if you cannot acquire a prescription for metformin, or cannot tolerate it due to digestive issues, there are nutrient formulas that have been shown to significantly boost AMPK activity.
Boost AMPK Activation Today
We here at Life Extension do not want you to age prematurely, waiting years for the results of the new FDA-approved human study. That’s why we recommend you initiate steps now to boost healthy AMPK activity today.
Below my signature are links to three of the many articles appearing around the world about the first clinical trial to see if metformin can slow aging and enable people to live longer.
To learn more about AMPK activation, please visit www.LifeExtension.com
For longer life,
Links to three articles about metformin and longevity: